Obesity has become a global epidemic disease as it is closely associated with a chronic low-grade inflammatory state that results in metabolic dysfunction. Ramulus Mori (Sangzhi) alkaloids (SZ-A) derived from L. were licensed to treat type 2 diabetes (T2DM) in 2020.
View Article and Find Full Text PDFNonalcoholic fatty liver disease (NAFLD), obesity, and type 2 diabetes mellitus (T2DM) have highly related mechanisms. (Sangzhi) alkaloids (SZ-A) from L. were approved in 2020 for the treatment of T2DM.
View Article and Find Full Text PDFSome FeS2 samples among metamorphic belt between coal and intrusion from Wolonghu mine in the north of Anhui Province were retrieved to characterize the signature of Raman Spectral. The results show that, all Raman data of different samples can be divided into 3 types as Ⅰ, Ⅱ and Ⅲ according to distinct differences of in Raman mode (M), Raman shift (Δν) and scattering intensity (Ⅰ). There are five strong scattering modes including high value Eg (1.
View Article and Find Full Text PDFHistone lysine methylation plays an important role in heterochromatin formation and reprogramming of gene expression. SET-domain-containing proteins are shown to have histone lysine methyltransferase activities. A large number of SET-domain genes are identified in plant genomes.
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