Publications by authors named "Qian-Wen Shang"
The prognostic value of 4L lymph node dissection (4L-LND) continues to be controversial. We conducted this systematic review and meta-analysis to evaluate the prognosis of 4L-LND in operable non-small-cell lung cancer (NSCLC) patients. We systematically searched studies from PubMed, Embase, and the Cochrane Library up to May 1, 2023.
View Article and Find Full Text PDFLymph node dissection is a vital part of surgical treatment for early-stage non-small cell lung cancer (NSCLC). Lobectomy with systematic lymph node dissection (SLND) still remains the gold standard surgical treatment for early-stage NSCLC patients. However, an increasing number of studies have demonstrated that lobe-specific lymph node dissection (L-SLND) can be used as an alternative therapy for SLND in carefully selected patients with early-stage NSCLC.
View Article and Find Full Text PDFBackground: Whether wedge resection or stereotactic body radiation therapy (SBRT) has better effectiveness in treatment of clinical stage I non-small cell lung cancer (NSCLC) patients remains unclear. Here we conducted the first meta-analysis to directly compare the survival outcomes of clinical stage I NSCLCs treated with wedge resection and SBRT.
Methods: We systematically searched studies from PubMed, Embase, and Corchrane Library up to October 1, 2021.
Article Synopsis
- The P1/HC-Pro viral suppressor from potyvirus inhibits posttranscriptional gene silencing (PTGS) and can be cleaved into two functional proteins, P1 and HC-Pro, with P1 enhancing HC-Pro's suppressive effects.
- A comparative transcriptome analysis of transgenic plants showed that P1/HC-Pro affects the accumulation of abscisic acid (ABA) and disrupts related signaling pathways, which influences gene responses to various stresses like drought and cold.
- The study found that crosstalk between ABA and other signaling pathways (jasmonic and salicylic acid) plays a role in modulating stress responses, and the analysis confirmed the effectiveness of using both high-throughput
Article Synopsis
- A new fungal clade, Trichoderma formosa, produces a peptide called Epl1 that enhances plant immunity when pre-treated on Nicotiana benthamiana, providing resistance against Tomato mosaic virus (ToMV).
- The research utilized deep sequencing to analyze transcriptomes, revealing that Epl1 is a 736 nucleotide-long transcript coding for a 12-kDa peptide.
- Challenges in identifying crucial genes for Epl1-mediated immunity were addressed through bioinformatics and gene network analysis, highlighting important signaling pathways and candidate genes for further research on plant immune responses.