Publications by authors named "Qian-Lin Zhang"
Dysfunction of learning and memory is widely found in many neurological diseases. Understanding how to preserve the normal function of learning and memory will be extremely beneficial for the treatment of these diseases. However, the possible protective effect of minocycline in memory impairment is unknown.
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- Etomidate, a common anesthetic, has been linked to cognitive deficits post-surgery, though the exact mechanisms remain unclear.
- Researchers conducted a study on 30 rats to investigate these cognitive impairments, focusing on spatial memory and neuronal health.
- Results showed that etomidate-treated rats exhibited significant impairments in spatial learning and memory, without causing neuronal death or oxidative stress, but demonstrated reduced levels of immediate early genes in the hippocampus.
Our goal was to determine whether local injections of vasoactive intestinal peptide (VIP) promote early stages of regeneration after nerve transection. Sciatic nerves were transected bilaterally in 2 groups of 10 adult mice. In the first group, 15 microg (20 microL) of VIP were injected twice daily into the gap between transected ends of the right sciatic nerve for 7 days (4 mice) or 14 days (6 mice).
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