[Correlation research on the expression of FcgammaR II b on B cells and rheumatoid arthritis patients of Shen deficiency syndrome].

Objective: To study the correlation between the expression of Fcgamma receptor II b (FcgammaRII b) on B cells and rheumatoid arthritis (RA) patients of Shen deficiency syndrome (SDS).

Methods: There were 43 RA patients, including 26 of SDS and 17 of non-SDS. The expression levels of FcgammaRII b on naive B cells, memory B cells, and plasma blasts in the peripheral blood were detected by flow cytometry.

[Correlation study of auto-immune antibodies and rheumatoid arthritis patients of Shen deficiency syndrome].

Objective: To investigate the correlation between auto-immune antibodies and rheumatoid arthritis (RA) patients of Shen deficiency syndrome (SDS), thus providing clinical evidence for further researches on molecular biological mechanisms of RA patients of SDS.

Methods: Totally 451 RA patients were assigned to the SDS group and the non-SDS group. Their general conditions (including gender, age, duration, and age of onset), C reactive protein (CRP), erythrocyte sedimentation rate (ESR), platelet (PLT), disease activities (DAS28), auto-antibodies [rheumatoid factor (RF), anti-CCP antibodies, anti-nuclear antibody (ANA)] were compared between the two groups.

[Pharmacological mechanisms of ethyl acetate extraction of Tongbiheji for active T cell signaling molecules].

Aim: To confirm extracts of activity from Traditional Chinese Medicine TongBiHeJi, study effect on two signaling pathways of T cells and clarify the pharmacological mechanisms of TongBiHeJi.

Methods: Concanavalin(ConA) were added successively into rats lymphocytic culture with different extracts of activity from Traditional Chinese Medicine. After 24 hours, CD71 expression rate on rat T lymphocytes activated with ConA was analyzed by flow cytometry.