Publications by authors named "Qian Q Liu"
Article Synopsis
- CPEB3 is highlighted as a key regulator in learning and memory, supported by various studies on behavior, brain activity, and brain structure.
- The review discusses CPEB3's interaction with important proteins like AMPA and NMDA receptors, actin, and PSD95, which are vital for synaptic plasticity.
- It also explores the molecular mechanisms influencing CPEB3's functions, including regulatory proteins, modifications, and structural features essential for its role in sustaining synaptic changes linked to long-term memory.
5-HT plays a crucial role in the progress and adjustment of pain both centrally and peripherally. The therapeutic action of the 5-HT receptors` agonist and antagonist in neuropathic pain have been widely reported in many studies. However, the specific roles of 5-HT subtype receptors have not been reviewed comprehensively.
View Article and Find Full Text PDFMajor depressive disorder takes at least 3 weeks for clinical anti-depressants, such as serotonin selective reuptake inhibitors, to take effect, and only one-third of patients remit. Ketamine, a kind of anaesthetic, can alleviate symptoms of major depressive disorder patients in a short time and is reported to be effective to treatment-resistant depression patients. The rapid and strong anti-depressant-like effects of ketamine cause wide concern.
View Article and Find Full Text PDFJatropha multifida is a medicinal plant that belongs to the Euphorbiaceae family. Our investigation revealed that the chloroform extract of J. multifida stems showed anti-melanin deposition activity against α-melanocyte stimulating hormone (α-MSH)- and 3-isobutyl-1-methylxanthine (IBMX)-induced melanogenesis in the mouse melanoma cell line (B16-F10).
View Article and Find Full Text PDFTrichoderma spp. are among the most widely recognized biocontrol fungi used to inhibit pathogens and promote plant growth. These functions are related to primary and secondary metabolites.
View Article and Find Full Text PDFObjective: To confirm the potential therapeutic efficacy of HAO472 against inflammatory bowel disease (IBD), we investigated the modulatory functions of HAO472 in a mouse model of trinitrobenzene sulfonic acid (TNBS)-induced colitis.
Methods: Colitis was induced via an intrarectal injection of TNBS in mice. HAO472 (5.