The synergy of tea tree oil nano-emulsion and antibiotics against multidrug-resistant bacteria.

Aims: We determined the synergistic effects of tea tree essential oil nano-emulsion (nanoTTO) and antibiotics against multidrug-resistant (MDR) bacteria in vitro and in vivo. Then, the underlying mechanism of action of nanoTTO was investigated.

Methods And Results: Minimum inhibitory concentrations and fractional inhibitory concentration index (FICI) were determined.

Eugenol alleviates Salmonella Typhimurium-infected cecal injury by modulating cecal flora and tight junctions accompanied by suppressing inflammation.

Background: Salmonella enterica serovar Typhimurium (ST) mainly exists in poultry and poultry related products, which are common sources of human salmonellosis. So, ST is an important zoonotic pathogen that threatens public health and safety. Eugenol has been noted for its antibacterial and anti-inflammatory properties, and it is expected to develop into an antibacterial therapy in vivo.

Bactericidal activity of gallic acid against multi-drug resistance Escherichia coli.

The continuous emergence of multidrug-resistant (MDR) bacteria has posed an increasingly serious public health threat which urges people to develop some alternatives. Gallic acid (GA) is a natural ingredient in many traditional Chinese medicines, which has many biological activities, such as antibacterial, and antiseptic. Here, clinical isolates of MDR Escherichia coli (E.

Tea Tree Oil Nanoemulsion Potentiates Antibiotics against Multidrug-Resistant .

Extensive efforts are underway to overcome the rising prevalence of antibiotic resistance. Combination therapy may be a potential method to treat multidrug-resistant (MDR) bacterial infections. In this study, tea tree essential oil (TTO) nanoemulsion (nanoTTO) was used in combination with antibiotics to kill microbes.

Effect of the bacterial community on the volatile flavour profile of a Chinese fermented condiment - Red sour soup - During fermentation.

Red sour soup (RSS) is a traditional fermented seasoning used by people in Guizhou Province, China. The volatile compounds were detected by gas chromatography ion mobility spectrometry (GC-IMS), while the bacterial community compositions were revealed by 16S sequencing. A total of 70 volatile substances were assessed, and esters, terpenes, and alcohols played a dominant role in RSS.

The protective effect and potential mechanisms of eugenol against Salmonella in vivo and in vitro.

Salmonella enterica serovar Typhimurium (S. Typhimurium) continues to be a serious concern to the poultry industry as a bacterial foodborne zoonosis, which generally results in intestinal inflammation and barrier dysfunction or even death. Eugenol is a phenolic compound with various pharmacological activities involved antioxidant, anti-inflammatory, and antibacterial effects, which is expected to be an effective nonantibiotic therapy.

Eugenol exposure in vitro inhibits the expressions of T3SS and TIF virulence genes in Salmonella Typhimurium and reduces its pathogenicity to chickens.

Background: Salmonella enterica serovar Typhimurium (S. Typhimurium) is a common food-borne pathogen, which has the ability to infect a wide range of hosts. The increasing emergence of drug-resistant strains urgently requires new alternative therapies.

Hydrothermal-template synthesis and electrochemical properties of CoO/nitrogen-doped hemisphere-porous graphene composites with 3D heterogeneous structure.

Despite the high capacity of CoO employed in lithium-ion battery anodes, the reduced conductivity and grievous volume change of CoO during long cycling of insertion/extraction of lithium-ions remain a challenge. Herein, an optimized nanocomposite, CoO/nitrogen-doped hemisphere-porous graphene composite (CoO/N-HPGC), is synthesized by a facile hydrothermal-template approach with polystyrene (PS) microspheres as a template. The characterization results demonstrate that CoO nanoparticles are densely anchored onto graphene layers, nitrogen elements are successfully introduced by carbamide and the nanocomposites maintain the hemispherical porous structure.