Publications by authors named "Qi-zhong Gao"
Objectives: To evaluate the diagnostic value and reproducibility of T2 mapping versus apparent diffusion coefficients (ADC) for identifying malignant lymph nodes in patients with non-mucinous rectal adenocarcinoma.
Methods: High-resolution magnetic resonance imaging, diffusion-weighted imaging, and T2 mapping were performed on patients with suspected metastatic lymph nodes in the mesorectum or around the superior rectal artery with a short-axis diameter of 4-10 mm. The T2 and ADC values of pathology-confirmed metastatic versus non-metastatic lymph nodes were compared using the independent-samples t test and receiver operating characteristic curves.
Article Synopsis
- AMPD2 is an enzyme that influences energy supply and metabolism in smooth muscle, and its role in colorectal cancer (CRC) has not been well understood until now.
- Research showed that AMPD2 is significantly overexpressed in CRC tissues compared to normal tissues, and its expression is linked to the Notch signaling pathway, which is crucial for cancer progression.
- High levels of AMPD2 in CRC are associated with more advanced tumors and poorer patient outcomes, suggesting that it could serve as a new prognostic biomarker for CRC.
[Significance and expression of p53, p21(Cip1/WAF1) and Gadd45α in breast neoplasm tissues].
Zhonghua Yi Xue Za Zhi
September 2012
Objective: To explore the expression and significance of p53, p21(Cip1/WAF1) and Gadd45α protein in breast cancer and their correlations with clinicopathologic features and prognosis in breast cancer.
Methods: The expressions of p53, p21(Cip1/WAF1) and Gadd45α proteins were determined by immunohistochemical staining. The relationship between these three proteins and clinicopathologic features in breast cancer was analyzed by χ(2) test and Spearman's rank correlation analysis.