Publications by authors named "Qi-xiang Yu"

Article Synopsis
  • The study investigates how steel slag can be used as a substrate for rooting cuttings, aiming to create a mixed substrate that utilizes solid waste effectively while replacing traditional cutting substrates.
  • Various substrates with 10% to 40% steel slag were analyzed for their physical and chemical properties, and their effects on rooting 'Red Beauty' cuttings were compared to conventional substrates (peat and perlite).
  • Results indicated that the 20% steel slag substrate (T) yielded superior root growth and development, having the highest performance in several metrics, while also showing better properties such as higher pH and conductivity compared to traditional substrates.
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Sphingomyelin synthase (SMS) is a key enzyme in sphingomyelin biosynthetic pathway, whose activity is highly related to the atherosclerosis progression. SMS2 could serve as a promising therapeutic target for atherosclerosis. Based on the structure of lead compound D2, a series of oxazolopyridine derivatives were designed, synthesized, and their inhibitory activities against purified SMS1 and SMS2 enzymes were evaluated respectively.

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Sphingomyelin synthase (SMS) has been proved to be a potential drug target for the treatment of atherosclerosis. However, few SMS inhibitors have been reported. In this paper, structure-based virtual screening was performed on hSMS1.

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Objectives: To compare the sensitivity of mammogram and breast dedicated MRI in detecting ductal carcinoma in situ with microinvaion (DCIS-MI) and ductal carcinoma in situ (DCIS) lesions, and to further investigate the independent predictive factors of mammogram and MRI sensitivity.

Methods: From August 2009 to November 2011, 122 consecutive confirmed breast cancer patients who had received operations were recruited for this clinical research. These patients were divided into two groups including DCIS (72 cases) and DCIS-MI (50 cases) based on pathologic reports.

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