[Immunohistochemical and morphometrical study on the expression of interleukin-10 (IL-10) in different expressive parts during cutaneous wound healing in mice].

Objective: To explore the expression of interleukin-10 (IL-10) in different expressive parts and its relationship with the wound age during cutaneous wound healing in mice.

Methods: Immunohistochemical and morphometrical analysis methods were performed on vital skin wounds.

Results: In normal and injury mouse skin IL-10 immunoreactivity was observed in epidermal cells.

[A study on the relationship between the expression of apoptosis-related gene and the injury time in earlier period following cerebral contusion].

Objective: To investigate the relationship between the expressive variety of apoptosis-related gene Bcl-2, Fas and the brain injury time during earlier period after cerebral contusion.

Methods: The morphologia feature of brain tissue was observed under microscopy and immunohistochemistry, image analyze technique was applied to detected the expression of Bcl-2 and Fas.

Results: Typical apoptotic cells were seen 8 hours after cerebral contusion.

[Trauma brain injury and apoptosis].

The evidence and the feature of apoptosis following tyrauma brain injury(TBI) and the possible mechanisms underlying apoptosis were reviewed. Recently research showed that apoptosis play an important role in TBI, the occurring time and area of apoptosis were found significant differences compared with that of necrosis. The neural cell apoptosis can undergo following many pathways after TBI.

[The research and application of vascular endothelial factor].

Vascular endothelial growth factor (VEGF) is a mult-effective catokines on the endothelial cells specificly. It promotes the endothelial cells to split multiply proliferate and metastasis. It increases vascular permeability and accelerates new vascular generation.