Publications by authors named "Qi-jia Xuan"
Pathol Oncol Res
July 2014
Article Synopsis
- Tumor-associated macrophages (TAMs) are linked to increased blood vessel growth and worse outcomes in breast cancer, but their specific role in tamoxifen resistance is not fully understood.
- A study examined 100 breast cancer tissues, comparing tamoxifen-resistant samples (48) to tamoxifen-sensitive ones (52), finding higher levels of EGFR and CD163+ macrophages in the resistant group.
- The presence of CD163+ macrophages was positively associated with larger tumors, lymph node metastasis, and patient obesity, with higher macrophage density correlating to a quicker recurrence or metastasis.
