Publications by authors named "Qi-fu Tan"
Background: The ketogenic diet (the KD) is an effective treatment for intractable epilepsy, especially in the paediatric population, and a growing number of studies have shown the neuroprotective role of the KD. However, few studies focused on the neuroprotective effects of the KD in traumatic brain injury (TBI). The present study aimed to investigate the effects of the KD on TBI.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to analyze changes in the amplitude of low-frequency fluctuations (ALFF) in resting-state functional MRI scans of patients with mesial temporal lobe epilepsy (mTLE) and bilateral hippocampal sclerosis (HS).
- Researchers compared ALFF data from 20 mTLE patients to that of 20 healthy volunteers, identifying regions of the brain with increased and decreased ALFF using statistical analysis.
- Results showed that mTLE patients displayed symmetrical increases in ALFF in areas related to limbic function and neocortex, while decreases were found in regions associated with the default mode network, suggesting that altered brain activity may influence the generation and spread of epileptic seizures.
Article Synopsis
- The study aimed to develop a technique for identifying areas in the brain that can cause epilepsy using fMRI, without needing to record brain waves through EEG.
- Researchers analyzed resting fMRI data from 12 epilepsy patients using independent component analysis and functional connectivity analysis to identify brain activity changes.
- Results showed that the new method accurately located pathological brain areas in all patients, confirming its effectiveness in mapping brain functions associated with epilepsy without needing simultaneous EEG recordings.