[Expression and significance of DNA methyltransferase in sera of patients with lung cancer].

Objective: To explore the protein expressions of DNMT1, DNMT3a and DNMT3b in sera of lung cancer patients.

Methods: Enzyme-linked immunosorbent assay (ELISA) method was used to measure the protein expressions of DNMT1, DNMT3a and DNMT3b in 136 lung cancer patients hospitalized at Department of Respiratory Diseases, First Affiliated Hospital, Zhengzhou University during September 2012 to June 2013. And 147 healthy controls were selected from a population of physical examination at Sixth People's Hospital of Zhengzhou.