[Significance of soluble P-selectin in diagnosis of pre-disseminated intravascular coagulation state in children with severe pneumonia].

Objective: Inflammation and coagulation occur concomitantly in severe pneumonia. The term non-overt disseminated intravascular coagulation (DIC) (pre-DIC state) refers to a state prevalent before the occurrence of overt DIC. It is suggested that initiation of treatment in non-overt DIC leads to better outcome than in overt DIC.