Aims: Our aim was to search for clinical predictors of good glycemic control in patients starting or intensifying oral hypoglycemic pharmacological therapy.
Methods: A multicenter, prospective cohort of 499 diabetic subjects was enrolled in this study: patients with newly diagnosed diabetes (NDM group) or poor glycemic control with oral antidiabetic drugs (OADs) (PDM group). All subjects then started or intensified OADs therapy and followed up for 91 days.
Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson's disease. Programming of the stimulation parameters is important for maintaining the efficacy of deep brain stimulation. Voltage is considered to be the most effective programming parameter.
View Article and Find Full Text PDFZhongguo Ying Yong Sheng Li Xue Za Zhi
August 2002
Aim: To investigate whether free fatty acid impair insulin signaling proteins to inhibit insulin action in rat islet cells.
Methods: After rat islet cells were incubated with palmitate (0.25 mmol/L) or oleate (0.