Publications by authors named "Qi-Wu Zhao"
Int J Biol Sci
October 2022
Article Synopsis
- Circular RNAs (CircRNAs), particularly hsa_circ_0003823, are being investigated for their roles in cancer, specifically in esophageal squamous cell carcinoma (ESCC) and its resistance to the drug Apatinib.
- The study used RNA sequencing and various assays to show that hsa_circ_0003823 is elevated in ESCC tissues and is linked to poor patient outcomes, promoting tumor growth and spread.
- By targeting microRNA-607, hsa_circ_0003823 enhances the expression of CRISP3, leading to reduced sensitivity to Apatinib, highlighting a potential therapeutic target for overcoming drug resistance in ESCC.
