Publications by authors named "Qi-Qiang Long"

Article Synopsis
  • The study evaluates how mutations affect treatment response and long-term survival in newly-diagnosed acute promyelocytic leukemia (APL) patients treated with all-trans retinoic acid and arsenic trioxide.
  • Analysis of 90 patients revealed a 20% mutation rate, with higher white blood cell counts and early death rates in those with mutations, particularly in high-risk groups.
  • Patients with mutations showed significantly lower event-free survival and overall survival rates after five years, indicating that addressing early death may improve outcomes for these individuals.
View Article and Find Full Text PDF

Two D-π-A-π-D type solvatochromic fluorescence probes (JT1 and JT2) based on triphenylamine have been synthesized. The photophysical and electrochemical properties of these probes as well as their solvatochromic behavior were studied. The Stokes shifts of JT1 and JT2 reach 175 nm (6417.

View Article and Find Full Text PDF

Acute basophilic leukemia (ABL), as a rare form of acute myeloid leukaemia (AML) accounts for <1% of cases of AML. ABL has not been detected for encouragingly specific targets. Here we report a de novo fragile ABL case treated with decitabine based regimen with transient response even if overall survival was a 3-month.

View Article and Find Full Text PDF

Fatty acid synthase (FASN) is a common phenotype to many kinds of human cancers, such as those of the breast, ovary, pancreas, prostate, colon, and so on. Increased FASN levels have been detected in the serum of the patients with breast and pancreatic cancers. The relationship between the FASN level in serum and the clinicopathological characteristics of colorectal cancer is investigated in this study.

View Article and Find Full Text PDF