Goodyschle A, a new butenolide with significant BchE inhibitory activity from .

Goodyschle A (), a new butenolide, was isolated from the whole grass of , an orchidaceous edible medicinal plant. The structure of the new compound was elucidated by 1 D and 2 D NMR experiments in addition to HRESIMS analyses. Compound was evaluated for its bioactivities including cytotoxic activity against human gastric cancer (SGC-7901) and human hepatocellular carcinoma (HepG2) cell lines, inhibitory activity on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), and DPPH radical scavenging activity.

Bioactivity-Guided Isolation of Cytotoxic Phenanthrenes from Spiranthes sinensis.

Bioactivity-guided separation led to the isolation of six novel phenanthrenes, spiranthesphenanthrenes A-F (1-6), together with 19 known compounds, including seven phenanthrenes (7-13), one bibenzyl compound (14), five flavonoids (15-16 and 20-22), and six simple phenolic compounds (17-19 and 23-25), from the petroleum ether (PE) and ethyl acetate (EtOAc) extracts of Spiranthes sinensis (Pers.) Ames, an edible medicinal plant named "panlongshen" in Chinese that is popularly used in medicinal foods and herbal teas. The structures of the obtained compounds were identified on the basis of extensive NMR spectroscopy and HR-ESI-MS analyses.

New biphenanthrenes with butyrylcholinesterase inhibitory activitiy from .

Encouraged by the potent inhibitory activity on butyrylcholinesterase (BChE) of 95% ethanol extract of (D. Don) Makino tubers, a further phytochemical investigation on tubers was conducted, which led to the isolation of a pair of new biphenanthrene atropisomers, namely cremaphenanthrene F-G (-). Their structures were elucidated on the basis of extensive spectroscopic analyses and chemical method.

Bioactivity-guided isolation of biphenanthrenes from Liparis nervosa.

Three new biphenanthrenes, Liparisphenanthrenes A-C (1-3), along with three known ones were obtained from the ethanolic extract of Liparis nervosa (Orchidaceae) by bioactivity-guided fractionation. Their structures were elucidated on the basis of extensive spectroscopic analysis. All the compounds obtained were tested in vitro for cytotoxic activities against stomach (HGC-27) and colon (HT-29) cancer cell lines.

[Chemical Constituents from Goodyera schlechtendaliana].

Objective: To study the chemical constituents of Goodyera schlechtendaliana.

Methods: Compounds were isolated through various chromatographic techniques and identified by spectroscopic analysis and comparison with those in literature.

Results: Seven compounds were obtained from 95% ethanol extract.