Publications by authors named "Qi-Li Yuan"

Article Synopsis
  • This study compared three methods for apicectomy—NINJA piezoelectric device, diamond bur, and Er: YAG laser—focusing on temperature rise, time taken, and cut quality.
  • Results showed the piezoelectric method had the highest temperature increase and took the longest time, while the laser methods showed better cut quality with fewer cracks and less smear layer formation.
  • The study concluded that Er: YAG laser and rotary instruments are efficient and safer alternatives for apicectomy compared to piezoelectric devices, suggesting that further research is needed to confirm the laser's effectiveness in real-life applications.
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To evaluate the effects of Hydroxypropyl methylcellulose acetate succinate(HPMCAS MF) on absorption of silybin(SLB) from supersaturable self-nanoemulsifying drug delivery system which was pre-prepared at the early stage experiment. The cell toxicity of self-emulsifying preparation was evaluated by the MTT method, and the in vitro membrane permeability and absorption promoting effect of the self-emulsifying preparation were evaluated by establishing a Caco-2 cell monolayer model. The in vivo and in vitro supersaturation correlation was evaluated via the blood concentration of SLB.

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Article Synopsis
  • The study aimed to assess the preparation methods of extracts from Linggui Zhugan Decoction by comparing four different processing techniques.
  • Results indicated that processes 2 and 4 produced extracts with characteristics and components similar to the traditional method (process 1), while process 3 showed significant differences and higher content levels in certain quality control components.
  • The findings suggest that processes 2 and 4 are effective alternatives to the traditional preparation of extracts, maintaining desirable quality standards.
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In order to improve the supersaturation and maintenance time of drug dispersion in curcumin self-nanoemulsion(CUR-SNEDDS), precipitation inhibitors(PPIs) were introduced to prepare curcumin supersaturated self-emulsion(CUR-SSNEDDS). The composition of CUR-SNEDDS prescriptions was selected through the solubility test, the compatibility of oil phase and surfactant, the investigation of the emulsifying ability of the surfactant and the drawing of the pseudo-ternary phase diagram. Analytic hierarchy process was used in combination with central composite design-response surface method to optimize the prescription.

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A non-exclusion paternity case with a mismatch in the autosomal short tandem repeats (STR) locus FGA is reported. The genotypes of the suspected father, the mother and the questioned child in FGA locus were 18/25, 20/26 and 20/22, respectively. Examination of 38 autosomal STR loci revealed no mismatches, and the paternity index is up to 1.

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