Publications by authors named "Qi-Jun Wu"
Background: Previous studies have examined the associations between individual foods or nutrients, but few studies have considered dietary patterns associated with ovarian cancer (OC) survival.
Methods: In a prospective cohort study, we examined the association between pre-diagnosis and post-diagnosis overall diet, including changes from pre-diagnosis to post-diagnosis, and overall survival (OS) in 560 patients with OC. Dietary intake was collected using a valid 111-item food frequency questionnaire.
Background: Diet and genetic risk are risk factors for colorectal cancer (CRC). The interaction between the EAT (Lancet Commission on healthy diets from sustainable food systems)-Lancet diet and genetic variants on CRC risk remains unclear.
Objectives: We aim to investigate the association between EAT-Lancet diet and CRC risk and to evaluate its combined effect with genetic risk on CRC risk.
Phthalates have been reported to increase the risk of various hormone-dependent cancers. However, there is still a lack of evidence regarding the association between phthalates and overall survival (OS) in advanced high-grade serous ovarian cancer (HGSOC). This study investigated the relationship between urinary phthalate metabolites and OS in patients with HGSOC using a nested case-control study within the Ovarian Cancer Follow-Up Study.
View Article and Find Full Text PDFBackground: Dietary factors impact systemic inflammation, which not only correlates with poorer outcomes in patients with ovarian cancer (OC) but also promotes cancer development through increased cell division, genetic alterations, and malignant transformation of epithelial cells at inflammatory sites. However, evidence between dietary inflammatory patterns and OC survival remains sparse.
Objective: The aim of this study was to examine associations between pre- and post-diagnosis dietary inflammatory patterns, including their changes, and overall survival (OS).
Background: The evidence on the relationship of dietary antioxidant nutrients with the survival of ovarian cancer (OC) remains scarce.
Objective: This study aimed to investigate these associations in a prospective cohort of Chinese patients with OC.
Methods: In this prospective cohort study, patients with epithelial OC completed a food frequency questionnaire at diagnosis and 12 months post-diagnosis, and were followed from 2015 to 2023.
Background: Although evidence suggests that perfluoroalkyl and polyfluoroalkyl substances (PFASs) are positively correlated to several disease risks, no studies have proven if plasma PFASs are related to ovarian cancer survival.
Objective: To explore the association between plasma PFASs and high-grade serous ovarian cancer (HGSOC) overall survival (OS) in the population who did not smoke.
Methods: We conducted a nested case-control study within the Ovarian Cancer Follow-Up Study, matching 159 dead patients and 159 survival ones based on body mass index, sample date, and age at diagnosis.
Dietary protein intake and PM on ovarian cancer survival: A prospective cohort study.
Ecotoxicol Environ Saf
February 2025
Background: Evolving evidence suggests both protein consumption and particulate matter less than 2.5 micrometers (PM) might be related to ovarian cancer (OC) mortality. However, no epidemiological studies have explored their potential interaction.
View Article and Find Full Text PDFWhole utilization of okara has important economic value, but there are two technical barriers: coarse mouthfeel caused by insoluble dietary fiber (IDF) and undesirable "beany" off-odors. UV-A irradiation and/or microbial fermentation were used to modify okara. The results indicated that single and combined treatments increased the soluble dietary fiber (SDF) content.
View Article and Find Full Text PDFBackground: Ovarian cancer (OC) is a heterogeneous malignancy with multiple histological subtypes, showing global variability in incidence. Temporal changes in diagnostic criteria and risk factors might influence the incidence and distribution of OC and its subtypes.
Methods: This study analyzed incidence patterns (2013-2017) and trends (1988-1992 to 2013-2017) of OC and its subtypes across 65 and 40 countries, respectively.
The present study aims to summarize the current biomarker landscape in gynecological cancers (GCs) and incorporate bioinformatics analysis to highlight specific biological processes. The literature was retrieved from PubMed, Web of Science, Embase, Scopus, Ovid Medline, and Cochrane Library. The final search was conducted on December 7, 2022.
View Article and Find Full Text PDFBackground: Numerous prospective cohort studies have investigated the influence of dietary patterns on the risks of various cancers, although the findings differed.
Objectives: To evaluate the associations of dietary patterns with risks of various cancers and assess the strength and validity of the evidence.
Methods: Relevant articles were retrieved from the PubMed, EMBASE, Web of Science, and Cochrane library databases from inception to February 22, 2024.
Purpose: Although (poly)phenols have shown potential in anti-cancer activities, their impact on improving ovarian cancer (OC) survival remains unknown. Therefore, we aim to first investigate the association between dietary polyphenol intake and OC survival, providing valuable insights into potential interventions.
Methods: The prospective cohort recruited 560 patients with OC to assess the associations of polyphenol intake, not only pre- and post-diagnosis but also the change from pre- to post-diagnosis with OC survival.
Article Synopsis
- Environmental pollution, specifically heavy metals, may negatively impact the prognosis of advanced high-grade serous ovarian cancer (HGSOC), but current evidence is limited.
- A study involving 159 deceased HGSOC patients and 159 matched living patients analyzed urinary levels of five heavy metals—arsenic, cadmium, chromium, mercury, and lead—using statistical models to determine associations with overall survival (OS).
- The results showed significant links between high levels of arsenic, cadmium, mercury, and lead in urine and poorer OS, with lead being the most influential in negatively affecting survival, indicating a need for further research.
Depression is highly prevalent in haemodialysis patients, and diet might play an important role. Therefore, we conducted this cross-sectional study to determine the association between dietary fatty acids (FA) consumption and the prevalence of depression in maintenance haemodialysis (MHD) patients. Dietary intake was assessed using a validated FFQ between December 2021 and January 2022.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates the link between adverse pregnancy outcomes and cancer risk in mothers and their children, highlighting a growing concern about these health issues.
- - A systematic review of various databases identified 129 meta-analyses, finding significant associations between factors like birth weight and cancers such as breast and leukemia, with moderate certainty in the evidence.
- - The authors conclude that while there are promising connections between certain adverse pregnancy outcomes and cancer risks, further research is necessary to strengthen these associations and address potential biases.
Article Synopsis
- Meta-analyses have shown mixed results regarding the relationship between whole blood cell count-derived indexes (NLR, PLR, LMR) and cancer prognosis, highlighting the need for a clearer understanding of the evidence quality.* ! -
- The review analyzed 694 associations from 224 articles, revealing that 97.8% of these studies were rated as moderate to high quality based on AMSTAR criteria.* ! -
- Although there were four associations with strong evidence, many others were only suggestive, indicating a need for further research to clarify these relationships and determine causality.* !
Background: There is currently a lack of comprehensive evidence regarding the correlation between Alternate Mediterranean Diet (AMED) and the survival of patients with ovarian cancer (OC). This prospective cohort study first assessed the association of AMED, not only pre-diagnosis and post-diagnosis but also the change from pre-diagnosis to post-diagnosis with OC survival.
Methods: A total of 560 OC patients were included in the study, and their dietary intake was assessed using a reliable 111-item food frequency questionnaire.
Background: Ambient air pollution might serve as a prognostic factor for ovarian cancer (OC) survival, yet the relationships between plant-based diet indices (PDIs) and OC survival remain unclear. We aimed to investigate the associations of comprehensive air pollution and PDIs with OC survival and explored the effects of air pollution-diet interactions.
Methods: The present study encompassed 658 patients diagnosed with OC.
Article Synopsis
- - The study investigated the links between diet quality, as measured by the Healthy Eating Index-2020 (HEI-2020), and survival rates in ovarian cancer patients over a follow-up period until February 2023.
- - It involved 1082 ovarian cancer patients aged 18-79, assessing their dietary habits before and after their diagnosis using a validated food questionnaire.
- - Results indicated that higher diet quality scores led to better overall survival rates, while a decline in diet quality after diagnosis was linked to worse survival outcomes.
: Macronutrients are the main part of the human diet and can affect multiple health outcomes. Nevertheless, associations between dietary macronutrient quality and asthenozoospermia risk have not been reported to date. Thus, this study aimed to be the first to explore the associations between macronutrient quality and asthenozoospermia risk using the novel multidimensional macronutrient quality index (MQI).
View Article and Find Full Text PDFBackground: Numerous meta-analyses have explored the association between the triglyceride-glucose (TyG) index and diverse health outcomes, yet the comprehensive assessment of the scope, validity, and quality of this evidence remains incomplete. Our aim was to systematically review and synthesise existing meta-analyses of TyG index and health outcomes and to assess the quality of the evidence.
Methods: A thorough search of PubMed, EMBASE, and Web of Science databases was conducted from their inception through to 8 April 2024.
Background: Numerous studies have been conducted to investigate the relationship between ABO and Rhesus (Rh) blood groups and various health outcomes. However, a comprehensive evaluation of the robustness of these associations is still lacking.
Methods: We searched PubMed, Web of Science, Embase, Scopus, Cochrane, and several regional databases from their inception until Feb 16, 2024, with the aim of identifying systematic reviews with meta-analyses of observational studies exploring associations between ABO and Rh blood groups and diverse health outcomes.
Article Synopsis
- The text reviews existing research on the connections between human papillomavirus (HPV) and various cancers, beyond the well-known anogenital and oropharyngeal cancers, highlighting inconsistencies in previous findings.
- An umbrella review was conducted, covering 31 systematic reviews and meta-analyses, and assessed the quality and credibility of the evidence using established tools.
- Findings revealed that while most studies had moderate to high quality, only one HPV type (HPV-18) showed convincing evidence for increased breast cancer risk, whereas HPV was found to be a highly suggestive risk factor for several other cancers, including oral and lung cancer.
Article Synopsis
- Research shows that per- and polyfluoroalkyl substances (PFASs) have possible links to various health issues, but more studies are needed for conclusive findings.
- A systematic review examined 157 meta-analyses assessing PFAS health impacts, indicating moderate-to-high quality results for most studies, particularly highlighting significant associations with low birth weight and immune response.
- While strong evidence connects some PFASs to specific health outcomes, many associations still lack certainty, with a substantial number of potential health effects needing further investigation.