Publications by authors named "Qi-Hang Li"
Clinical application of the widely used chemotherapeutic agent, doxorubicin (DOX), is limited by its cardiotoxicity. Mitochondrial dysfunction has been revealed as a crucial factor in DOX-induced cardiotoxicity. 7,8,3'-Trihydroxyflavone (THF) is a mimetic brain-derived neurotrophic factor with neuroprotective effects.
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- The study examines how 7,8-Dihydroxyflavone (7,8-DHF) can help protect heart cells (cardiomyocytes) from damage caused by mitochondrial dysfunction linked to cardiovascular diseases.
- Researchers used rotenone, a compound that inhibits mitochondrial function, to simulate this dysfunction in heart cells and found that 7,8-DHF significantly reduced cell death and improved mitochondrial health.
- The findings suggest that 7,8-DHF works by enhancing energy production in mitochondria, reducing harmful reactions, and promoting the activation of a protein called p-STAT3, highlighting its potential as a new treatment for heart-related mitochondrial issues.
On account of the intralayer and interlayer heterogeneity, high temperature (110 °C), and high salinity (224,919 mg/L) of Tahe channel sand reservoir, single profile control or chemical flooding cannot greatly enhanced oil recovery. The goal of the current research was to optimize a polymer gel formula that was suitable for high-temperature and high-salinity reservoirs, screen an appropriate chemical flooding method, and determine the efficiency of the combination of profile control and chemical flooding. Experimental results indicated that the formed polymer gel could maintain relatively high strength after aging for 30 days.
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