Longitudinal associations of high-density lipoprotein cholesterol or low-density lipoprotein cholesterol with metabolic syndrome in the Chinese population: a prospective cohort study.

Objective: Currently, most studies only reveal the relationship between baseline high-density lipoprotein cholesterol (HDL-c) or low-density lipoprotein cholesterol (LDL-c) levels and metabolic syndrome (MetS). The relationship between dynamic changes in HDL-c or LDL-c and MetS remains unclear. We aimed to gain a deeper understanding of the relationship between the dynamic changes in HDL-c or LDL-c and MetS.

Birth defects data from surveillance hospitals in Dalian city, China, 2006-2010.

Objective: The objective of this study is to disclose characteristics of birth defects in perinatal infants in Dalian and provide an epidemiological basis for controlling birth defects.

Methods: Data used in this study were collected from surveillance hospitals in Dalian during 2006-2010. Comparison analysis and trend analysis were conducted by performing Chi-square tests.

[Cost-effectiveness analysis on the once-in-a-lifetime cervical cancer screening program for women living in rural and urban areas of China].

Objective: To estimate the cost-effectiveness of once-in-a-lifetime cervical cancer screening program and to predict the optimal modality for its operation on women living in rural and urban areas of China, based on Markov modeling and simulation.

Methods: Three modalities including visual inspection with acetic acid plus Lugol's iodine (VIA/VILI), conventional Pap Smear (Pap Smear), and simple HPV DNA testing (careHPV) were hypothesized for the rural cohort, whereas other five modalities including Pap Smear, liquid-based cytology (LBC), simple HPV DNA testing (careHPV), Hybrid Capture 2 HPV DNA testing (HC2), and LBC plus HC2 (LBC + HC2) were tested for the urban cohort. A Markov model was constructed based on the factors as natural history, screening, diagnosis and treatment on cervical cancer using data related to the epidemics and the costs from rural and urban areas of the country.

[Report of 3162 cases of holmium laser enucleation of the prostate and review].

Objective: To evaluate the safety, effectiveness, and outcomes of holmium laser enucleation of the prostate (HoLEP) for patients with symptomatic enlarged prostate after 11 years of experience.

Methods: The 3162 evaluable patients treated with holmium laser enucleation of the prostate at our institution between August 2001 and August 2011 were retrospectively analyzed. Study variables included International Prostate Symptom Score, quality of life, maximum urinary flow rate, and incidence of complications.

Selective transurethral resection of the prostate combined with transurethral incision of the bladder neck for bladder outlet obstruction in patients with small volume benign prostate hyperplasia (BPH): a prospective randomized study.

Purpose: Transurethral resection of the prostate (TURP) has a high failure rate in patients with small volume benign prostate hyperplasia (BPH) with bladder outlet obstruction (BOO). We describe and report the results of an alternative surgical method, selective transurethral resection of the prostate (STURP) in combination with transurethral incision of the bladder neck (TUIBN).

Methods: Patients were randomized to receive TURP or STRUP+TUIBN in combination with TUIBN.

[Effectiveness and health economic analysis of strategies on cervical cancer screening and early diagnosis and treatment].

Objective: To explore the appropriate strategies which are suitable for the areas with diverse health and economic resource settings in China by estimating the life outcomes and cost-effectiveness of several cervical cancer screening strategies.

Methods: Markov model was used to calculate the long-term effectiveness, utility, benefit and cost among screened and unscreened cohorts in rural and urban areas, and then analyses of cost-effectiveness, cost-utility and cost-benefit were performed. The assessed screening strategies were acetic acid of visual inspection combined with Lugol's iodine staining (VIA/VILI), conventional Pap smear and simple HPV DNA testing (careHPV) in rural areas, and conventional Pap smear, simple HPV DNA testing (careHPV), HPV DNA testing (HC2) and liquid-based cytology (LBC) alone or combined with HPV DNA testing (LBC+HC2) in urban areas.

Dynamic anthropometric changes in children as shown by longitudinal data for 2004-2009 from the city of Dalian, China.

Background: The physical development of children and adolescents always attracts widespread attention in society.

Aim: The goal of the present study was to systematically analyse the dynamic changes in some anthropometric characteristics among primary school age children.

Subjects And Methods: Using a longitudinal study design, this study monitored physical growth annually in 933 pupils of Dalian, China, from 2004-2009.

B-vitamin consumption and the prevalence of diabetes and obesity among the US adults: population based ecological study.

Background: The global increased prevalence of obesity and diabetes occurred after the worldwide spread of B-vitamins fortification, in which whether long-term exposure to high level of B vitamins plays a role is unknown. Our aim was to examine the relationships between B-vitamins consumption and the obesity and diabetes prevalence.

Methods: This population based ecological study was conducted to examine possible associations between the consumption of the B vitamins and macronutrients and the obesity and diabetes prevalence in the US population using the per capita consumption data from the US Economic Research Service and the prevalence data from the US Centers for Disease Control and Prevention.

[Holmium laser enucleation of the prostate].

Holmium laser enucleation of the prostate (HoLEP), as a new hi-tech introduced from abroad, may bring about exactly the same results as open surgery, and is even superior to transurethral resection of the prostate (TURP), especially in handling the front prostate, with its advantages of minimal invasiveness, better safety, shorter operation time, less blood loss, and quicker recovery, which can be achieved through peeling off the prostate alongside the external sphincter and getting it removed in three parts or as a whole. So far, the author has accomplished more than 3 000 surgeries using this technique, without any serious complications. Any patient that can accept anesthesia and endoscopic surgery can be treated by HoLEP.

Chronic niacin overload may be involved in the increased prevalence of obesity in US children.

Aim: To investigate nicotinamide's action on glucose metabolism, and the association between niacin consumption and obesity prevalence.

Methods: Dynamic nicotinamide's effect on plasma hydrogen peroxide and glucose metabolism was investigated using oral glucose tolerance tests with or without nicotinamide in the same five healthy subjects. Lag-regression analysis was used to examine the association between the niacin consumption and the obesity prevalence among US children using the data from the Economic Research Service of the US Department of Agriculture and from US Centers for Disease Control and Prevention, respectively.