Publications by authors named "Qi-Chang Wan"
Article Synopsis
- This study aimed to assess how effective fibroblast activation protein inhibitors (FAPI) PET/CT imaging is for identifying lymph node metastases in lung cancer patients compared to standard FDG PET/CT.
- A total of seven studies with 409 patients were analyzed, finding that FAPI PET/CT had a pooled sensitivity of 88% and specificity of 94%, outperforming FDG PET/CT, which had a sensitivity of 78% and specificity of 66%.
- The results suggest that FAPI PET/CT provides excellent diagnostic accuracy for detecting lymph node metastases, which could potentially decrease the need for invasive tests in lung cancer patients.
Objective: To analyze the incidence and associated factors of hypothyroidism after radioiodine treatment for hyperthyroidism during a 13-year follow-up period.
Subjects And Methods: This was a retrospective study of consecutive patients with hyperthyroidism who were treated using a single dose of radioactive iodine (RAI) with a calculated dose regimen from 07/2005 to 12/2012. Univariate and multivariate Cox regression models were used to examine the factors that are associated with the occurrence of hypothyroidism after RAI therapy.
Objective: To investigate the value of Ga-PSMA-11 positron emission tomography/computerized tomography (PET/CT) in evaluating lacrimal and salivary glands function.
Methods: Ten patients with pSS and 18 healthy volunteers were recruited in this study. All participants underwent Ga-PSMA-11 PET/CT, and the patients with pSS performed salivary gland scintigraphy the next day.
Could thyroidectomy be excluded if 18F-FDG-PET suggests benignity for TNIC?
Endocr Relat Cancer
February 2021
We read with interest the article by Rosario et al., which summarized the practical applicability of accessible imaging method in the management of thyroid nodules with indeterminate cytologically (TNIC) (Rosario, et al. 2021).
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- A systematic review and meta-analysis were conducted to compare the diagnostic accuracy of dual-phase 99mTc-MIBI SPECT/CT and 4D CT for finding hyperfunctioning parathyroid glands.
- The analysis included nine studies with 911 participants, revealing that 4D CT had better sensitivity (0.85) than SPECT/CT (0.68) but slightly lower specificity (0.93 vs. 0.98).
- Although 4D CT showed improved sensitivity, its clinical use is limited by its high radiation exposure and lower specificity, while contrast-enhanced SPECT/CT might enhance sensitivity without affecting specificity.