Electrochemical lithium storage of a biactive organic molecule containing cyano and imine groups.

With an electron-deficient rigid planar structure and excellent π-π stacking ability, hexaazatriphenylene (HAT) and its derivatives are widely used as basic building blocks for constructing covalent organic frameworks (COFs), components of organic light-emitting diodes and solar cells, and electrode materials for lithium-ion batteries (LIBs). Here, a HAT derivative, hexaazatriphenylenehexacarbonitrile, is explored as an anode material for LIBs. The HAT anode exhibited high initial reversible capacities of 672 mA h g at 100 mA g and 550 mA h g at 400 mA g and stable cycling with a capacity of 503 mA h g after 1000 cycles at 400 mA g corresponding to a capacity retention of 91.

Efficacy and Safety of Placebo During the Maintenance Therapy of Ovarian Cancer in Randomized Controlled Trials: A Systematic Review and Meta-analysis.

Introduction: This meta-analysis evaluated the efficacy and safety of placebo during the maintenance therapy of ovarian cancer (OC) patients in randomized controlled trials (RCTs).

Methods: A comprehensive literature review was performed for RCTs published up to and including August 2020 from four electronic databases. We analyzed the efficacy and safety in the control arms of the maintenance therapy in advanced OC patients.

Selective estrogen receptor modulator with estrogen does not affect the proliferation and apoptosis of uterine leiomyoma cells.

Background: The administration of menopausal hormone therapy (MHT) in women with uterine leiomyomas is still debated. The purpose of this article is to study the proliferation and apoptosis of uterine leiomyoma cells under the impact of selective estrogen receptor modulator (SERM) combined with estrogen.

Methods: Primary cultured uterine leiomyoma cells in the perimenopausal period were treated with estrogen (17-beta estradiol) + SERM (raloxifene) as the tissue selective estrogen complex (TSEC) group, while both estrogen + medroxyprogesterone acetate (E+P) and estrogen (E) alone as were used as control groups.

Improved antimelanogenesis and antioxidant effects of polysaccharide from Cuscuta chinensis Lam seeds after enzymatic hydrolysis.

Cuscuta chinensis polysaccharide (CPS) was extracted using hot water and enzymatically hydrolyzed C. chinensis polysaccharide (ECPS) was produced by the mannase enzymatic hydrolysis process. The purpose of this research was to investigate the antimelanogenic activity of ECPS and CPS in B16F10 melanoma cells.

Koninginins R-S from the endophytic fungus Trichoderma koningiopsis.

Two new metabolites named koninginins R-S (1-2) were isolated from the culture of Trichoderma koningiopsis YIM PH30002. Their chemical structures were elucidated by the extensive spectroscopic analysis. These isolated compounds showed certain antifungal activities against phytopathogens, Fusarium flocciferum and Fusarium oxysporum.

Perineal leiomyoma in a postmenopausal woman: A case report.

Leiomyomas in the female reproductive system are commonly located in the uterus and typically regress following the menopause. Vulval leiomyomas are rare, and to the best of our knowledge, perineal leiomyomas in postmenopausal women have not been previously reported in the literature. The present case describes a 60-year-old Chinese woman who experienced perineal tenderness and lumbosacral radiating pain.

The influence of hydrogen peroxide initiator concentration on the structure of eucalyptus lignosulfonate.

In order to improve lignin-based materials' utilization, the grafting mechanism of lignin was studied by investigating hydrogen peroxide (H2O2) initiator's effect on the structure of eucalyptus lignosulfonate calcium (HLS). HLS was treated by low content of H2O2 (H2O2/HLS(wt)=1%, 2%, 4%) under various reaction temperature and time. Changes in HLS structure were investigated by difference UV, UV, FTIR, (1)H NMR, GPC and intrinsic viscosity.

In vitro-activated tumor-bearing host T cells and the effectiveness of tumor vaccine immunotherapy.

Background And Objective: Vaccination during periods of lymphopenia may facilitate immune responses to weak self-antigens and enhance antitumor immunity. The objective of this study was to determine the effectiveness of tumor vaccine immunotherapy combined with immune reconstruction using tumor-bearing host immune cells in lymphopenia, and to investigate the role of tumor-bearing host T cells activated in vitro during immunotherapy.

Design And Setting: Animal study conducted in the First Affiliated Hospital of Xi'an Jiaotong University from January 2009 to January 2010.

[Evaluation of immune reconstitution with in vitro-activated T cells from a tumor-bearing host].

Aim: To evaluate the reconstituted immune system with in vitro-activated T cells from tumor-bearing rats coupled with ovarian cancer vaccination.

Methods: Fischer 344 female rats were injected with cyclophosphamide (CY) as a lymphopenia (LP) model. The immune systems of the rats were reconstituted with in vitro-activated T cells from the same individuals.

[Animal experiments of immunotherapy with ovarian tumor vaccine during lymphopenia induced by chemotherapy.].

Objective: To explore the mechanisms and effects of adoptive immunotherapy with ovarian cancer vaccine modified by GM-CSF gene which was used after immunologic reconstitution during lymphopenia induced by chemotherapy.

Methods: Lymphopenia was induced by chemotherapy with cyclophosphamide. The immune reconstituted model was built in rats.

Exvivo experiments of human ovarian cancer ascites-derived exosomes presented by dendritic cells derived from umbilical cord blood for immunotherapy treatment.

Objectives: Exosomes, a type of membrane vesicles, released from tumor cells have been shown to be capable of transferring tumor antigens to dendritic cells and activating specific cytotoxic T-lymphocytes. Recent work has demonstrated the presence of high numbers of exosomes in malignant effusions. Umbilical cord blood (UCB) is a rich source of hematopoietic stem cells and from which a significant number of dendritic cells can be produced.

Immune protection effect of exosomes against attack of L1210 tumor cells.

We investigated the anti-tumor immunity of L1210 cell-secreted exosomes. Exosomes were purified by ultrafiltration centrifugation and sucrose gradient ultracentrifugation. Expression of H-2D and interstitial cell adhesion molecule (ICAM(-1 was investigated by solid-phase immuno-electron microscopy and expression of Hsp70 was investigated by western blotting.

[Expression and its clinical significance of p27 protein in cervical carcinoma tissues].

Aim: To investigate the expression of p27 protein and its significance in cervical carcinoma tissues.

Methods: The p27 protein expression in 26 normal cervical tissues and 48 cervical carcinoma tissues was detected by streptavidin-peroxidase staining(SP method).

Results: The positive rate of p27 protein expression in 48 cervical carcinoma tissues was 39.