Publications by authors named "Qi Wen"

Objective: To investigate the effect of Emotional Freedom Techniques on anxiety, depression and sleep in older people living with HIV (PLWH).

Methods: 70 older PLWH experiencing anxiety, depression, and sleep disorders were randomly divided into control and experimental groups using a random number table system (RNT), with 35 participants in each group. The experimental group received Emotional Freedom Techniques once a day for 15-20 min as part of their routine care and health counselling, and the intervention lasted for 2 weeks.

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The cooccurrence of NPM1, FLT3-ITD, and DNMT3A mutations (i.e., triple mutation) is related to dismal prognosis in patients with acute myeloid leukemia (AML) receiving chemotherapy alone.

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Pyrethroid pesticide residues have detrimental effects on soil ecology and crop growth during insecticidal operations in agriculture. In this study, a novel strain VF-2 was isolated from long-term pesticide-treated cropland and had a maximum degradation efficiency of 81.66% for synthetic pyrethroid β-cypermethrin (β-CY) under optimized conditions.

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Objectives: Myasthenia Gravis (MG) is an autoimmune disorder that can exacerbate for various reasons, including vaccination and infection. This study aimed to investigate the safety of COVID-19 vaccines for MG patients, factors influencing MG exacerbation after COVID-19 infection (MECI), the course and prognosis of MECI, and the impact of COVID-19 vaccine on infected MG patients.

Methods: Patients were enrolled from the MG database in the Department of Neurology, Xuanwu Hospital, Capital Medical University.

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Background: Our previous small-sample study indicated that serum levels of interleukin enhancer binding factor 2 (ILF2) may have the potential for gastric cancer (GC) detection. The present study was conducted to further validate the diagnostic value of serum ILF2 protein for GC.

Methods: Serum specimens and clinical data were collected from patients with GC (n = 99) or benign gastric disease (BGD) (n = 49) and healthy controls (HC) (n = 51).

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Article Synopsis
  • The study aimed to understand how sennoside A behaves in the body after being administered either through injection or orally, using a validated liquid chromatography method for accurate measurement in rat plasma.
  • The method demonstrated strong reliability with a wide range for measurement accuracy and confirmed that sennoside A remains stable during the testing process.
  • Results showed that after oral administration in rats, sennoside A reaches peak concentration in about 2.9-3.6 hours, has a slow elimination rate, and exhibits low absolute bioavailability at just 0.9%-1.3%.
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The evaluation of an individual's mental health and behavioral functioning, known as psychological assessment, is generally conducted by a mental health professional. This process aids in diagnosing mental health conditions, identifying suitable treatment options, and assessing progress during treatment. Currently, national health systems are unable to cope with the constantly growing demand for such services.

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  • * High levels of the collagen receptor DDR2 are linked to worse survival rates in patients, and cancer cells exert mechanical forces in their surroundings, but the impact of DDR2 on these migration forces isn't fully understood.
  • * Research using a specially engineered neuroblastoma cell line showed that reducing DDR2 led to lower cell growth, stiffness, and traction forces on collagen substrates, indicating that targeting DDR2 could be beneficial for future treatments.
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A series of eight nitroxide compounds (four substituted piperidines, three pyrrolidines and one oxo-piperidine) are found to undergo electron transfer to 2'-deoxyribose-peroxyl and the guanyl radical. One-electron oxidation potentials of the nitroxides to oxoammonium cations (oxoammonium reduction potential), , have been measured against a common redox indicator, chlorpromazine, and found to span the range 751 ± 15 mV to 973 ± 15 mV. Fast chemical reduction of the 2'-deoxyribose-peroxyl radical to the hydroperoxide, generated by OH radical attack on 2-deoxyribose, dR, in oxygenated aqueous solution, is a redox-dependent reaction, with rate constants of 0.

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Surfactants, which are widely used in skin care products and cleansers, can cause skin irritation. The skin irritation potential of surfactants is fundamentally determined by their molecular structure and is directly related to their microscopic aggregation structure and specific interactions with the skin. The microscopic origin of the irritation of the surfactants remains unknown.

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Synthetic pyrethroids are widely used insecticides which may cause chronic diseases in non-target organisms upon long-term exposure. Microbial degradation offers a reliable method to remove them from the environment. This study focused on Brevibacillus parabrevis BCP-09 and its enzymes for degrading pyrethroids.

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Background: In 2021, an EULAR task force published a definition of difficult-to-treat rheumatoid arthritis (D2T RA). Our current knowledge of D2T RA with the EULAR definition is based on European and Asian cohorts, and no North American cohort has yet to be published. The aim of this study was to compare D2T RA patients to non-D2T RA who are good responders to advanced therapy, and to describe their evolution in an university health center patient cohort.

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Objective: To compare stillbirth rates and risks for small for gestational age (SGA), large for gestational age (LGA) and appropriate for gestational age (AGA) pregnancies at 24-44 completed weeks of gestation using a birth-based and fetuses-at-risk approachs.

Design: Population-based, multi-country study.

Setting: National data systems in 15 high- and middle-income countries.

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Drought is one of the natural stresses that greatly impact plants. Castor bean (Ricinus communis L.) is an oil crop with high economic value.

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This scoping review paper redefines the Artificial Intelligence-based Internet of Things (AIoT) driven Human Activity Recognition (HAR) field by systematically extrapolating from various application domains to deduce potential techniques and algorithms. We distill a general model with adaptive learning and optimization mechanisms by conducting a detailed analysis of human activity types and utilizing contact or non-contact devices. It presents various system integration mathematical paradigms driven by multimodal data fusion, covering predictions of complex behaviors and redefining valuable methods, devices, and systems for HAR.

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We aimed to identify the severity and duration of COVID-19 infection on complications after allo-HSCT. Enrolled 179 hospitalized patients with COVID-19 were categorized into long-term infection (> 18 days, n = 90) or short-term infection group (≤ 18 days, n = 89) according to the median duration of COVID-19. The severity of COVID-19 was categorized as asymptomatic infection, mild, moderate, severe, and critical illness according to guidelines of National Institutes of Health.

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Article Synopsis
  • Structural variants (SVs) are rarely found in Duchenne muscular dystrophy (DMD), which is usually characterized by deletions and point mutations in the DMD gene, making detection challenging with standard short-read sequencing.
  • A family case is presented where a boy with symptoms of muscular dystrophy had no visible abnormalities in the DMD gene using routine techniques, but analysis of dystrophin mRNA revealed missing exons 59 to 79.
  • Advanced long-read whole-genome sequencing ultimately identified a complex structural variant and a translocation within the DMD gene, highlighting the need to consider SVs in molecular diagnostics when other methods fail.
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The integration of advanced sensor technologies has significantly propelled the dynamic development of robotics, thus inaugurating a new era in automation and artificial intelligence. Given the rapid advancements in robotics technology, its core area-robot control technology-has attracted increasing attention. Notably, sensors and sensor fusion technologies, which are considered essential for enhancing robot control technologies, have been widely and successfully applied in the field of robotics.

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