Publications by authors named "Qi Lan"

The NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome plays an essential role in myocardial infarction (MI) development. Up to now, no bibliometric analyses of NLRP3 in MI have been performed. Publications related to NLRP3 in MI from 1 January 2013 to 20 August 2024 were extracted from the Web of Science Core Collection (WoSCC).

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Trait and situational forgiveness are vital coping mechanisms and stress responses in the face of interpersonal transgressions. The hypothalamic-pituitary-adrenal (HPA) axis plays a key role in regulating these strategies in response to such transgressions. Building on this foundation, Study 1 examined the impact of cumulative genetic effects of the HPA axis (i.

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Background: Myocardial infarction (MI) is a common critical syndrome in the late development of cardiovascular diseases (CVDs), and traditional Chinese Medicine (TCM) treatment has become an essential branch in this field.

Objective: This study aimed to use bibliometric methods to examine the research trajectory of TCM treatment of MI from 2007 to 2024 from a multidimensional perspective and analyse its characteristics, hotspots, and frontiers.

Methods: This study used the search formula TS OR TI OR AB OR A ("traditional Chinese medicine" or "Chinese medicine" or "TCM" or "traditional medicine, Chinese" or " Chinese traditional medicine" or "Chinese medicine, traditional") AND TS OR TI OR AB OR AK ("myocardial infarction" or "myocardial infarctions" or " infarction, myocardial" or "infarctions, myocardial" or "myocardial infarct" or "MI") to find the Web of Science Core Collection (WOSCC) of relevant studies from 01/01/2007 to 04/29/2024.

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Cardiovascular disease (CVD) is a leading cause of human mortality worldwide, with patients often at high risk of heart failure (HF) in myocardial infarction (MI), a common form of CVD that results in cardiomyocyte death and myocardial necrosis due to inadequate myocardial perfusion. As terminally differentiated cells, cardiomyocytes possess a severely limited capacity for regeneration, and an excess of dead cardiomyocytes will further stress surviving cells, potentially exacerbating to more extensive heart disease. The article focuses on the relationship between programmed cell death (PCD) of cardiomyocytes, including different forms of apoptosis, necrosis, and autophagy, and MI, as well as the potential application of these mechanisms in the treatment of MI.

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To overcome the limitations of optical coherence tomography (OCT) in imaging large-scale freeform objects, we propose a methodological framework that utilizes OCT as both a shape sensor and a tomographic imager in robotic scanning. Our approach integrates a deep-learning-based surface detection algorithm to counter OCT artifacts and an adaptive robotic arm pose adjustment algorithm for sensing and imaging uneven objects. We demonstrate the effectiveness and superiority of our method on various objects, achieving high-resolution, large-scale tomographic imaging that adeptly manages OCT artifacts and surface irregularities.

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Backgrounds: The influence of serotonin function on social phobia has been well-documented, yet the polygenic risk score of serotonergic polymorphisms for social phobia remains unclear.

Methods: We assessed two aspects of social phobia (i.e.

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Fiber-form optics extends the high-resolution tomographic imaging capabilities of optical coherence tomography (OCT) to the inside of the human body, i.e., endoscopic OCT.

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Article Synopsis
  • Bone marrow mesenchymal stem cells (BMSCs) exosomes have shown promise in treating heart injuries caused by ischemia/reperfusion, and this study investigates how Danshen decoction (DSD) enhances their therapeutic effects on such injuries in both lab settings and animal models.
  • * Researchers identified specific microRNAs (miRNAs) that were influenced by DSD and impacted the TXNIP signaling pathway, assessing the effectiveness of different treatments involving BMSCs-exosomes in rat models of myocardial injury.
  • * Results indicated that DSD pretreatment significantly increased the expression of certain miRNAs, particularly miR-93-5p, which in turn improved heart function and reduced cellular injury and inflammation associated with oxidative stress and apoptosis.*
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Macrophages - one of the crucial immune cells, are recruited to the cardiac tissue by chemokines, cytokines and upregulated endothelial adhesion molecules after myocardial infarction (MI). During the course of inflammation in the cardiac tissue, necrotic cells and matrix debris is phagocytosed by M1 macrophages. During the resolution phase of cardiac inflammation, M2 macrophages promote cardiac recovery.

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We present a protocol for the hierarchical controlled joint remote implementation of the partially unknown operations of m qudits belonging to some restricted sets by using m multiparticle high-dimensional entangled states as the quantum channel. All the senders share the information of the partially unknown operations and cooperate with each other to implement the partially unknown operations on the remote receiver's quantum system. The receivers are hierarchized in accordance with their abilities to reconstruct the desired state.

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  • The paper focuses on 3D multimodal medical image registration, which is crucial for medical analysis but complicated by differences in image types and high computational costs.
  • The study introduces a new network called DELR-Net, designed to be lightweight while effectively integrating advanced components for image processing.
  • Experimental results demonstrate that DELR-Net not only provides superior registration accuracy compared to existing methods but also shows better generalization across different image modalities with fewer parameters.
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  • Pueraria is a traditional food and medicinal plant in China, with puerarin being its key active ingredient known for its various health benefits, especially for the liver.
  • Recent research shows puerarin has hepatoprotective effects against liver diseases like metabolic dysfunction-associated steatosis, alcohol-related issues, and hepatic cancer, working through inflammation, oxidative stress, and more.
  • Despite its low bioavailability due to poor solubility, combining puerarin with advanced drug delivery systems could enhance its effectiveness, and it has demonstrated low toxicity, making it a promising candidate for liver disease treatment in clinical settings.
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The Hippo-yes-associated protein (YAP) signaling pathway plays a crucial role in cell proliferation, differentiation, and death. It is known to have impact on the progression and development of cardiovascular diseases (CVDs) as well as in the regeneration of cardiomyocytes (CMs). However, further research is needed to understand the molecular mechanisms by which the Hippo-YAP pathway affects the pathological processes of CVDs in order to evaluate its potential clinical applications.

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Article Synopsis
  • - Atherosclerosis is a chronic inflammatory disease affecting arteries, leading to high rates of illness and death, with defective autophagy and excessive reactive oxygen species (ROS) contributing to its progression.
  • - A new polymer, P5c, has been developed that promotes autophagy and delivers antioxidant enzymes like superoxide dismutase (SOD) and catalase (CAT) into macrophages to reduce ROS levels and prevent foam cell formation.
  • - In studies on ApoE mice, P5c, augmented by neutrophil membranes, shows strong anti-atherosclerosis effects by enhancing autophagy, reducing harmful cell infiltration in plaques, modifying macrophage behavior, and improving organ functionality.
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Proximal rotary scanning is predominantly used in the clinical practice of endoscopic and intravascular OCT, mainly because of the much lower manufacturing cost of the probe compared to distal scanning. However, proximal scanning causes severe beam stability issues (also known as non-uniform rotational distortion, NURD), which hinders the extension of its applications to functional imaging, such as OCT elastography (OCE). In this work, we demonstrate the abilities of learning-based NURD correction methods to enable the imaging stability required for intensity-based OCE.

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  • Attachment styles in emerging adults are linked to emotional regulation, stress management, and social connections.
  • Research focused on how genetic variations related to serotonin affect attachment behaviors over time, using data from college students.
  • Findings indicate that those with a higher genetic predisposition show greater attachment anxiety and avoidance, along with more variability in attachment styles.
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Aging causes degenerative changes in organs, leading to a decline in physical function. Over the past two decades, researchers have made significant progress in understanding the rejuvenating effects of young blood on aging organs, benefiting from heterochronic parabiosis models that connect the blood circulation of aged and young rodents. It has been discovered that young blood can partially rejuvenate organs in old animals by regulating important aging-related signaling pathways.

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  • This paper presents an improved VoxelMorph network, called RCV-Net, which enhances 3D multimodal unsupervised medical image registration by integrating ResNet modules and CBAM for better feature extraction.
  • RCV-Net addresses the speed and accuracy limitations of traditional registration techniques by incorporating a lightweight residual network that boosts learning without significantly increasing parameter size.
  • Experimental results show RCV-Net outperforms current methods in multimodal registration tasks, supported by evaluation metrics like SSIM, PSNR, and MSE, and demonstrates effective generalization on external databases.
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  • The study focuses on the role of the CRHR1 gene, which is important for hormone regulation in the brain related to stress and emotional responses, particularly in attachment behaviors.
  • Researchers analyzed a group of 604 freshmen to see how specific variations (polymorphisms) in the CRHR1 gene might influence the stability and changes in their attachment styles over time.
  • The findings indicate that certain variations (rs110402 and rs242924) are linked to stable attachment, but do not affect the variability of attachment styles among individuals.
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Background: Vitamin E has long been linked to skin health, including all of its possible functions in cosmetic products, to its roles in membrane integrity and even the aging process. However, reports on the relationship between serum vitamin E levels and the risk of chronic inflammatory skin diseases have been inconsistent. We performed a systematic review and meta-analysis to evaluate the association between serum vitamin E levels and chronic inflammatory skin diseases.

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Areca palm (Areca catechu L.; family Arecaceae) is an important tropical medicinal crop and is also used for masticatory and religious purposes in Asia. Improvements to areca properties made by traditional breeding tools have been very slow, and further advances in its cultivation and practical use require genomic information, which is still unavailable.

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Soluble microbial products (SMP), a type of polymers released from microbial metabolism and decay, show great potential for wastewater treatment as bioflocculants; however, biogenic flocculant utilization is currently limited to bacterial SMP. In this study, SMP produced by Phanerochaete chrysosporium BKMF-1767 (SMP-P) was investigated to determine the application potential of fungal SMP. SMP-P exhibited high flocculation activity in kaolin suspension at a dosage range of 0.

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Diabetic peripheral neuropathy (DPN) is a common complication of diabetes and axonopathy is its main pathological feature. Previous studies suggested an advantage of taurine against diabetes. However, there are few reports which study the effect of taurine against axonopathy.

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Article Synopsis
  • The paper introduces a new security mechanism called the VSSQR scheme, which combines visual secret sharing with QR codes to enhance payment security.
  • It involves creating two QR code shares from an original secret image, which contain merchant information.
  • By stacking these QR code shares, the original secret image can be revealed, and its consistency with the original determines the authenticity of the QR code for secure payments.
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