Publications by authors named "Qi Lan"
A two-sample study on the relationship between polygenic risk score of serotonergic polymorphisms and social phobia: Interpersonal adaptability as a mediator.
Prog Neuropsychopharmacol Biol Psychiatry
December 2024
Backgrounds: The influence of serotonin function on social phobia has been well-documented, yet the polygenic risk score of serotonergic polymorphisms for social phobia remains unclear.
Methods: We assessed two aspects of social phobia (i.e.
Fiber-form optics extends the high-resolution tomographic imaging capabilities of optical coherence tomography (OCT) to the inside of the human body, i.e., endoscopic OCT.
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- Bone marrow mesenchymal stem cells (BMSCs) exosomes have shown promise in treating heart injuries caused by ischemia/reperfusion, and this study investigates how Danshen decoction (DSD) enhances their therapeutic effects on such injuries in both lab settings and animal models.
- * Researchers identified specific microRNAs (miRNAs) that were influenced by DSD and impacted the TXNIP signaling pathway, assessing the effectiveness of different treatments involving BMSCs-exosomes in rat models of myocardial injury.
- * Results indicated that DSD pretreatment significantly increased the expression of certain miRNAs, particularly miR-93-5p, which in turn improved heart function and reduced cellular injury and inflammation associated with oxidative stress and apoptosis.*
Macrophages after myocardial infarction: Mechanisms for repairing and potential as therapeutic approaches.
Int Immunopharmacol
December 2024
Macrophages - one of the crucial immune cells, are recruited to the cardiac tissue by chemokines, cytokines and upregulated endothelial adhesion molecules after myocardial infarction (MI). During the course of inflammation in the cardiac tissue, necrotic cells and matrix debris is phagocytosed by M1 macrophages. During the resolution phase of cardiac inflammation, M2 macrophages promote cardiac recovery.
View Article and Find Full Text PDFWe present a protocol for the hierarchical controlled joint remote implementation of the partially unknown operations of m qudits belonging to some restricted sets by using m multiparticle high-dimensional entangled states as the quantum channel. All the senders share the information of the partially unknown operations and cooperate with each other to implement the partially unknown operations on the remote receiver's quantum system. The receivers are hierarchized in accordance with their abilities to reconstruct the desired state.
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- The paper focuses on 3D multimodal medical image registration, which is crucial for medical analysis but complicated by differences in image types and high computational costs.
- The study introduces a new network called DELR-Net, designed to be lightweight while effectively integrating advanced components for image processing.
- Experimental results demonstrate that DELR-Net not only provides superior registration accuracy compared to existing methods but also shows better generalization across different image modalities with fewer parameters.
Article Synopsis
- Pueraria is a traditional food and medicinal plant in China, with puerarin being its key active ingredient known for its various health benefits, especially for the liver.
- Recent research shows puerarin has hepatoprotective effects against liver diseases like metabolic dysfunction-associated steatosis, alcohol-related issues, and hepatic cancer, working through inflammation, oxidative stress, and more.
- Despite its low bioavailability due to poor solubility, combining puerarin with advanced drug delivery systems could enhance its effectiveness, and it has demonstrated low toxicity, making it a promising candidate for liver disease treatment in clinical settings.
The Hippo-yes-associated protein (YAP) signaling pathway plays a crucial role in cell proliferation, differentiation, and death. It is known to have impact on the progression and development of cardiovascular diseases (CVDs) as well as in the regeneration of cardiomyocytes (CMs). However, further research is needed to understand the molecular mechanisms by which the Hippo-YAP pathway affects the pathological processes of CVDs in order to evaluate its potential clinical applications.
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- - Atherosclerosis is a chronic inflammatory disease affecting arteries, leading to high rates of illness and death, with defective autophagy and excessive reactive oxygen species (ROS) contributing to its progression.
- - A new polymer, P5c, has been developed that promotes autophagy and delivers antioxidant enzymes like superoxide dismutase (SOD) and catalase (CAT) into macrophages to reduce ROS levels and prevent foam cell formation.
- - In studies on ApoE mice, P5c, augmented by neutrophil membranes, shows strong anti-atherosclerosis effects by enhancing autophagy, reducing harmful cell infiltration in plaques, modifying macrophage behavior, and improving organ functionality.
Proximal rotary scanning is predominantly used in the clinical practice of endoscopic and intravascular OCT, mainly because of the much lower manufacturing cost of the probe compared to distal scanning. However, proximal scanning causes severe beam stability issues (also known as non-uniform rotational distortion, NURD), which hinders the extension of its applications to functional imaging, such as OCT elastography (OCE). In this work, we demonstrate the abilities of learning-based NURD correction methods to enable the imaging stability required for intensity-based OCE.
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- Attachment styles in emerging adults are linked to emotional regulation, stress management, and social connections.
- Research focused on how genetic variations related to serotonin affect attachment behaviors over time, using data from college students.
- Findings indicate that those with a higher genetic predisposition show greater attachment anxiety and avoidance, along with more variability in attachment styles.
A new species, W.B.Ju, L.
View Article and Find Full Text PDFDeep learning-based 3D brain multimodal medical image registration.
Med Biol Eng Comput
February 2024
Article Synopsis
- This paper presents an improved VoxelMorph network, called RCV-Net, which enhances 3D multimodal unsupervised medical image registration by integrating ResNet modules and CBAM for better feature extraction.
- RCV-Net addresses the speed and accuracy limitations of traditional registration techniques by incorporating a lightweight residual network that boosts learning without significantly increasing parameter size.
- Experimental results show RCV-Net outperforms current methods in multimodal registration tasks, supported by evaluation metrics like SSIM, PSNR, and MSE, and demonstrates effective generalization on external databases.
Article Synopsis
- The study focuses on the role of the CRHR1 gene, which is important for hormone regulation in the brain related to stress and emotional responses, particularly in attachment behaviors.
- Researchers analyzed a group of 604 freshmen to see how specific variations (polymorphisms) in the CRHR1 gene might influence the stability and changes in their attachment styles over time.
- The findings indicate that certain variations (rs110402 and rs242924) are linked to stable attachment, but do not affect the variability of attachment styles among individuals.
Areca palm (Areca catechu L.; family Arecaceae) is an important tropical medicinal crop and is also used for masticatory and religious purposes in Asia. Improvements to areca properties made by traditional breeding tools have been very slow, and further advances in its cultivation and practical use require genomic information, which is still unavailable.
View Article and Find Full Text PDFSoluble microbial products (SMP), a type of polymers released from microbial metabolism and decay, show great potential for wastewater treatment as bioflocculants; however, biogenic flocculant utilization is currently limited to bacterial SMP. In this study, SMP produced by Phanerochaete chrysosporium BKMF-1767 (SMP-P) was investigated to determine the application potential of fungal SMP. SMP-P exhibited high flocculation activity in kaolin suspension at a dosage range of 0.
View Article and Find Full Text PDFDiabetic peripheral neuropathy (DPN) is a common complication of diabetes and axonopathy is its main pathological feature. Previous studies suggested an advantage of taurine against diabetes. However, there are few reports which study the effect of taurine against axonopathy.
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- The paper introduces a new security mechanism called the VSSQR scheme, which combines visual secret sharing with QR codes to enhance payment security.
- It involves creating two QR code shares from an original secret image, which contain merchant information.
- By stacking these QR code shares, the original secret image can be revealed, and its consistency with the original determines the authenticity of the QR code for secure payments.
A versatile nanoprobe for acetone vapor was designed and fabricated. It is based on the use of gold-doped three-dimensional (3D) hierarchical porous zinc oxide microspheres (Au/ZnO HPMSs). The nanoprobe was synthesized by annealing zinc hydroxide carbonate precursor (obtained by a hydrothermal method) doped with gold nanoparticles.
View Article and Find Full Text PDFB Lymphocytes Are Predictors of Insulin Resistance in Women with Gestational Diabetes Mellitus.
Endocr Metab Immune Disord Drug Targets
August 2019
Unlabelled: Backgroud: The present study aimed to investigate the association between immune cells and gestational diabetes mellitus (GDM) and identify a reasonable predictor of insulin resistance in women with GDM.
Objective: The clinical and biochemical characteristics of 124 women with GDM and 168 healthy pregnant women were compared.
Methods: The percentage of immune cells in the blood of the subjects was analyzed by flow cytometry.
A wild rice QTL qGL12.2 for grain length was fine mapped to an 82-kb interval in chromosome 12 containing six candidate genes and none was reported previously. Grain length is an important trait for yield and commercial value in rice.
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