Highly Efficient Capture of Heavy Metal Ions on Amine-Functionalized Porous Polymer Gels.

Porous polymer gels (PPGs) are characterized by inherent porosity, a predictable structure, and tunable functionality, which makes them promising for the heavy metal ion trap in environmental remediation. However, their real-world application is obstructed by the balance between performance and economy in material preparation. Development of an efficient and cost-effective approach to produce PPGs with task-specific functionality remains a significant challenge.

FeO@MIL-100(Fe) modified ZnS nanoparticles with enhanced sonocatalytic degradation of tetracycline antibiotic in water.

Sonocatalysis has attracted excellent research attention to eradicate hazardous pollutants from the environment effectively. This work synthesised an organic/inorganic hybrid composite catalyst by coupling FeO@MIL-100(Fe) (FM) with ZnS nanoparticles using the solvothermal evaporation method. Remarkably, the composite material delivered significantly enhanced sonocatalytic efficiency for removing tetracycline (TC) antibiotics in the presence of HO compared to bare ZnS nanoparticles.

Association of Sensory Impairment With Institutional Care Willingness Among Older Adults in Urban and Rural China: An Observational Study.

Background And Objectives: An aging population has contributed to increasing rates of sensory impairment (SI) among older adults and a boom in institutional elder care. However, little is known regarding the association between SI and institutional care willingness. This study identified the association between SI and institutional care willingness among older adults living both in urban and rural China.

Degradation of tetracycline by peroxymonosulfate activated with MnFeO-CNTs: Key role of singlet oxygen.

Tetracycline (TC) is a kind of electron-rich organic, and singlet oxygen (O) oxidative pathway-based advanced oxidation processes (AOPs) have represented outstanding selective degradation to such pollutants. In this paper, an excellent prepared strategy for O dominated catalyst was adopted. A catalyst composed of non-stoichiometric doping Mn-Fe bimetallic oxide supported on CNTs (0.

Comparative Efficacy of Teclistamab Versus Physician's Choice of Therapy in the Long-term Follow-up of APOLLO, POLLUX, CASTOR, and EQUULEUS Clinical Trials in Patients With Triple-class Exposed Relapsed or Refractory Multiple Myeloma.

Background: The efficacy and safety of teclistamab in patients with RRMM who received ≥3 prior lines of therapy and were triple-class exposed (TCE) are being evaluated in the single-arm, multicohort, phase I/II MajesTEC-1 trial (NCT04557098). We evaluated the comparative effectiveness of teclistamab versus physician's choice (PC) of therapy in TCE RRMM patients.

Methods: Individual patient-level data from MajesTEC-1 patients who received teclistamab (1.

Comparative analysis of volatile aromatic compounds from a wide range of pear (PyrusL.) germplasm resources based on HS-SPME with GC-MS.

Aroma is one of the most important sensory characteristics of fruit quality. Here, the aroma composition of mature fruits of 202 pear cultivars was detected by headspace solid-phase microextraction (HS-SPME) with gas chromatography-mass spectrometry (GC-MS). As a result, 221 major volatile components were detected, among which aldehydes, esters and alcohols were the most dominant aroma components.

BreedingEIS: An Efficient Evaluation Information System for Crop Breeding.

Crop breeding programs generate large datasets. Thus, it is difficult to ensure the accuracy and integrity of all the collected data in the breeding process. To improve breeding efficiency, we established an open source and free breeding evaluation information system (BreedingEIS).

Diurnal transcriptome dynamics reveal the photoperiod response of Pyrus.

Photoperiod provides a key environmental signal that controls plant growth. Plants have evolved an integrated mechanism for sensing photoperiods with internal clocks to orchestrate physiological events. This mechanism has been identified to enable timely plant growth and improve fitness.

[Study on the relationship between indexes of different abnormal weight and dyslipidemia in adults in Beijing City].

To analyze the relationship and consistency between indexes of different abnormal weight and dyslipidemia in adults in Beijing City. From August to December of 2017, 4 975 residents aged 18 to 79 years old in 5 districts of Beijing were randomly selected as subjects by using a multi-stage stratified cluster sampling method. Questionnaire, physical examination and laboratory tests were conducted.

Associations of granulocyte colony-stimulating factor with toxicities and efficacy of chimeric antigen receptor T-cell therapy in relapsed or refractory multiple myeloma.

Background Aims: Few studies have reported the associations of granulocyte colony-stimulating factor (G-CSF) with cytokine release syndrome (CRS), neurotoxic events (NEs) and efficacy after chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (R/R) multiple myeloma (MM). We present a retrospective study performed on 113 patients with R/R MM who received single anti-BCMA CAR T-cell, combined with anti-CD19 CAR T-cell or anti-CD138 CAR T-cell therapy.

Methods: Eight patients were given G-CSF after successful management of CRS, and no CRS re-occurred thereafter.

Effects of Extruded Corn with Different Gelatinization Degrees on Feed Preference, Growth Performance, Nutrient Digestibility, and Fecal Microbiota of Weaning Piglets.

Preference and performance trials were conducted to investigate the effects of extruded corn with different degrees of gelatinization on the feed preference, growth performance, nutrient digestibility, and fecal microbiota of weaning piglets. In the preference trial, 144 piglets who were 35 days old were weighed and allotted to six treatments with four replications per treatment. Piglets in each treatment group were allowed to choose two of the following four corn-supplemented diets: conventional corn (NC) or extruded corn with low (LEC; 41.

Anti-G Protein-Coupled Receptor, Class C Group 5 Member D Chimeric Antigen Receptor T Cells in Patients With Relapsed or Refractory Multiple Myeloma: A Single-Arm, Phase Ⅱ Trial.

Purpose: G protein-coupled receptor, class C group 5 member D (GPRC5D) is considered to be a promising surface target for multiple myeloma (MM) immunotherapy. Here, we report the efficacy and safety of anti-GPRC5D chimeric antigen receptor (CAR) T cells in patients with relapsed or refractory (R/R) MM.

Methods: This phase Ⅱ, single-arm study enrolled patients (18-70 years) with R/R MM.

Design, Synthesis, and Anti-Cancer Evaluation of Novel Cyclic Phosphate Prodrug of Gemcitabine.

ProTide and cyclic phosphate ester are two successful prodrug technologies to overcome the limitations of nucleoside drugs, among which the cyclic phosphate ester strategy has not been widely used in the optimization of gemcitabine. Herein, we designed a series of novel ProTide and cyclic phosphate ester prodrugs of gemcitabine. Cyclic phosphate ester derivative exhibits much higher anti-proliferative activity than positive control NUC-1031 with ICs of 3.

Octave-spanning soliton microcomb in silica microdisk resonators.

We demonstrate a chip-based octave-spanning soliton microcomb in a whispering gallery mode microresonator platform. By fabricating a silica microdisk resonator and optimizing its dispersion with dry etching, we achieve an octave-spanning single-soliton microcomb with a repetition rate of ∼670 GHz at an optical pump power of 162.6 mW.

Elucidation of the GAUT gene family in eight Rosaceae species and function analysis of PbrGAUT22 in pear pollen tube growth.

The phylogenetic relationship and evolutionary history of the GAUT gene family were identified in 8 Rosaseae species. PbrGAUT22 was involved in controlling pollen tube growth by regulating the content of pectins. In plants, galacturonosyltransferases (GAUTs) were involved in homogalacturonan biosynthesis and functioned in maintaining pollen tube cell wall integrity.

Sonocatalytic degradation of tetracycline hydrochloride with CoFeO/g-CN composite.

In this work, different mass percent ratios of CoFeO coupled g-CN (w%-CoFeO/g-CN, CFO/CN) nanocomposites were integrated through a hydrothermal process for the sonocatalytic eradication of tetracycline hydrochloride (TCH) from aqueous media. The prepared sonocatalysts were subjected to various techniques to investigate their morphology, crystallinity, ultrasound wave capturing activity and charge conductivity. From the investigated activity of the composite materials, it has been registered that the best sonocatalytic degradation efficiency of 26.

Ag NW-Embedded Coaxial Nanofiber-Coated Yarns with High Stretchability and Sensitivity for Wearable Multi-Sensing Textiles.

The emerging intelligent piezoresistive yarn/textile-based sensors are of paramount importance for skin-interface electronics, owing to their unparalleled features including softness, breathability, and easy integration with functional devices. However, employing a facile way to fabricate 1D sensing yarns with mechanical robustness, multi-functional integration, and comfortability is still demanded for satisfying the practical applications. Herein, a facile one-step synchronous conjugated electrospinning and electrospraying technique is innovatively employed to continuously construct an Ag NW-embedded polyurethane (PU) nanofiber sensing yarn (AENSY) with hierarchical architecture.

[The Efficacy and Safety of Daratumumab-Based Regimen in Treatment of Multiple Myeloma Patients with Renal Impairment].

Objective: To investigate the efficacy and safety of daratumumab in treatment of multiple myeloma (MM) patients with renal impairment (RI).

Methods: The clinical data of 15 MM patients with RI who received daratumumab-based regimen from January 2021 to March 2022 in three centers were retrospectively analyzed. Patients were treated with daratumumab or daratumumab combined with dexamethasone or daratumumab combined with bortezomib and dexamethasone and the curative effect and survival were analyzed.

Introduction of multilayered magnetic core-dual shell SERS tags into lateral flow immunoassay: A highly stable and sensitive method for the simultaneous detection of multiple veterinary drugs in complex samples.

Direct, convenient, and sensitive monitoring of the residues of multiple drugs in complex environments is important but remains a challenge. Here, we report a surface-enhanced Raman scattering (SERS)-based multiplexed lateral flow immunoassay (LFA) that supports the simultaneous and sensitive detection of commonly used drugs kanamycin, ractopamine, clenbuterol, and chloramphenicol in unprocessed complex samples through the dual signal amplification strategy of numerous efficient hotspots and magnetic enrichment. Multilayered magnetic-core dual-shell nanoparticles (MDAu@Ag) with controllable subtle nanogaps were fabricated via the polyethyleneimine-mediated layer-by-layer (LBL) assembly of two layers of Au@Ag satellites onto superparamagnetic FeO cores and conjugated with specific antibodies as multifunctional tags in the LFA system for rapid capture, separation, and quantitative analysis.

Copper indium sulfide quantum dots in photocatalysis.

Since the advent of photocatalytic technology, scientists have been searching for semiconductor materials with high efficiency in solar energy utilization and conversion to chemical energy. Recently, the development of quantum dot (QD) photocatalysts has attracted much attention because of their unique characteristics: small size, quantum effects, strong surface activity, and wide photoresponse range. Among ternary chalcogenide semiconductors, CuInS QDs are increasingly examined in the field of photocatalysis due to their high absorption coefficients, good matching of the absorption range with sunlight spectrum, long lifetimes of photogenerated electron-hole pairs and environmental sustainability.

A large-scale proteogenomic atlas of pear.

Pear is an important fruit tree that is widely distributed around the world. The first pear genome map was reported from our laboratory approximately 10 years ago. To further study global protein expression patterns in pear, we generated pear proteome data based on 24 major tissues.