Color correction methods for underwater image enhancement: A systematic literature review.

Underwater vision is essential in numerous applications, such as marine resource surveying, autonomous navigation, objective detection, and target monitoring. However, raw underwater images often suffer from significant color deviations due to light attenuation, presenting challenges for practical use. This systematic literature review examines the latest advancements in color correction methods for underwater image enhancement.

ITGA8 deficiency in hepatic stellate cells attenuates CCl-Induced liver fibrosis via suppression of COL11A1.

Background And Objective: Liver fibrosis is a pathological process driven by chronic liver injury, characterized by excessive extracellular matrix (ECM) deposition due to hepatic stellate cell (HSC) activation. Integrins are critical regulators of ECM remodeling and HSC activation, yet the role of integrin α8(ITGA8) in liver fibrosis remains unclear. This study aims to investigate the function and underlying mechanisms of HSC-derived ITGA8 in liver fibrosis and evaluate the therapeutic potential of ITGA8-targeted intervention.

Polymicrobial interactions of and its role in the process of oral diseases.

Objective:  infection affects approximately 50% of the global population. The predominant route of transmission is through the oral pathway, making the oral cavity highly significant in its infection. This review focuses on the relationship between  and oral diseases, the influence of  infection on the oral microbiota, and the potential mechanisms involving certain oral pathogens.

Jianpi Qingre Tongluo Prescription (Huangqin Qingrechubi Capsule) alleviates inflammation and hypercoagulability by inhibiting the JAK2/STAT3 pathway via CircRNA 104633 downregulation in gouty arthritis.

Ethnopharmacological Relevance: Gouty arthritis (GA) is characterized by intermittent inflammatory pain, which dramatically compromises the quality of life of patients. Huangqin Qingrechubi Capsule (HQC) is an empirical traditional Chinese medicine prescription used to treat GA for over 20 years, with favorable efficacy. However, little is known about the specific mechanism of action of HQC in GA treatment.

Profilin Pfy1 is critical for cell wall integrity and virulence in .

Profilin is a small actin-binding protein that plays an important role in actin polymerization. However, its functions in , the most prevalent fungal pathogen, remain unclear. Here, we report that profilin plays a crucial role in morphogenesis and virulence.

Analysis of the Alkaline Resistance Mechanism of Halomonas alkalicola CICC 11012 s by Proteomics and Metabolomics.

In recent years, as excellent industrial microorganisms, Halomonas has become a potential chassis cell of the next generation of industrial biotechnology because of its advantages of low complexity, antipollution ability, and rapid fermentation. Therefore, there is an urgent need to study the genome information, synthetic biology, multiomics, and other technologies of Halomonas, and it is also highly important to study its tolerance to extreme environments. Halomonas alkalicola CICC 11012 s is the most alkaliphilic bacterium in the genus Halomonas and is an excellent alkali-resistant bacterium that was independently isolated in our laboratory; this bacterium plays a certain role in industrial pollution control and the application of synthetic biology chassis cells.

Clinical, biological, and neuroimaging profiles for motoric cognitive risk syndrome in older adults: The MIND-China study.

Background: Motoric cognitive risk syndrome (MCR) has been associated with dementia, functional dependence, and mortality. We sought to describe the prevalence and distribution of MCR and to explore the clinical, biological, and neuroimaging profiles for MCR in rural-dwelling Chinese older adults.

Methods: This population-based study included 5021 dementia- and disability-free participants (mean age 70.

Obesity reduces the urate-lowering efficacy among patients with primary gout: a prospective cohort study.

Objectives: Obesity affects 53% of gout patients, while its effect on urate-lowering therapy (ULT) is unclear. This study aimed to compare the response to febuxostat among different body mass index (BMI) catalogs of male gout patients.

Methods: A prospective study recruited 633 men with gout, classified by BMI into normal-weight, overweight, and obese groups.

Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma ≤3 cm in Potentially Transplantable Patients: A Over 10-Year Survival Study.

Background: Salvage liver transplantation is promising for hepatocellular carcinoma(HCC) recurrence post-ablation but is significantly affected by recurrence beyond Milan Criteria (RBM).

Materials And Methods: A retrospective cohort study of potentially transplantable HCC patients undergoing ablation between 2007 and 2017 assessed median time to recurrence beyond Milan Criteria(TRBM) via Kaplan-Meier curves and predictive capacity of recurrence and RBM for overall survival(OS) via Receiver Operating Characteristic Curves, and identified independent risk factors for TRBM and RBM via Cox and binary logistic regression models.

Results: We enrolled 191 potentially transplantable patients with early-stage HBV-related HCC ≤3 cm who underwent ablation.

Investigation on the occupational situation of clinical research associates in China.

Clinical research associates (CRAs) are the sponsor's representatives, monitor the process and quality of clinical trials, their professional quality can affect the quality of clinical trials. But there is a conflict between the large number of CRAs personnel and unsatisfactory quality of clinical trial monitoring, and the reason is unknown. Therefore, our study investigated the occupational status of CRAs through a questionnaire survey.

Long-Term Time in Target Range for Systolic Blood Pressure Since Childhood and Midlife Arterial Stiffness.

Background: Elevated blood pressure (BP) in childhood is associated with adult hypertension and arterial stiffness. However, the effect of long-term time in target range (TTR) for BP since childhood on the risk of arterial stiffness in midlife remains unclear.

Objectives: The purpose of this study was to determine the independent association of TTR for systolic blood pressure (SBP) from childhood to midlife with arterial stiffness in adulthood.

Silica Nanoparticle-Protein Aggregation and Protein Corona Formation Investigated with Scattering Techniques.

Protein-nanoparticle interactions and the resulting corona formation play crucial roles in the behavior and functionality of nanoparticles in biological environments. In this study, we present a comprehensive analysis of protein corona formation with superfolder green fluorescent protein (sfGFP) and bovine serum albumin in silica nanoparticle dispersions using small-angle X-ray scattering (SAXS) and dynamic light scattering (DLS). For the first time, we subtracted the scattering of individual proteins in solution and individual nanoparticles from the protein-nanoparticle complexes.

A Nomogram Built on Clinical Factors and CT Attenuation Scores for Predicting Treatment Response of Acute Myeloid Leukemia Patients.

Acute myeloid leukemia (AML) is an aggressive cancer with variable treatment responses. While clinical factors such as age and genetic mutations contribute to prognosis, recent studies suggest that CT attenuation scores may also predict treatment outcomes. This study aims to develop a nomogram combining clinical and CT-based factors to predict treatment response and guide personalized therapy for AML patients.

Thompson Sampling for Non-Stationary Bandit Problems.

Non-stationary multi-armed bandit (MAB) problems have recently attracted extensive attention. We focus on the abruptly changing scenario where reward distributions remain constant for a certain period and change at unknown time steps. Although Thompson sampling (TS) has shown success in non-stationary settings, there is currently no regret bound analysis for TS with uninformative priors.

Instantaneous self-recovery and ultra-low detection limit hydrogel electronic sensor for temporomandibular disorders intelligent diagnosis.

Temporomandibular disorders (TMD) intelligent diagnosis promises to elevate clinical efficiency and facilitate timely TMD management for patients. However, development of TMD intelligent diagnostic tools with high accuracy and sensitivity presents challenges, particularly in sensing minute deformations and ensuring rapid self-recovery. Here we report a biocompatible hydrogel electronic sensor with instantaneous self-recovery (within 2.

Tetrahedral Framework Nucleic Acid (tFNA)-Loaded Metformin (Met) Modulates Cellular Pyroptosis and AMPK to Ameliorate Type II Diabetic Periodontitis.

Diabetic periodontitis presents a unique therapeutic challenge, primarily due to its chronic inflammatory profile and the associated bone loss driven by immune dysregulation. Metformin (Met) is recognized for its potent anti-inflammatory properties, yet its limited cellular uptake has hindered its clinical effectiveness in diabetic periodontitis. A tetrahedral framework nucleic acid (tFNA)-based delivery system is developed to enhance Met cellular uptake and investigate its effects on diabetic periodontitis in this study.

Preventive effects of taxifolin on dental caries in vitro and in vivo.

Objectives: The present study aimed to explore the inhibitory effect of taxifolin (TAX) on Streptococcus mutans (S. mutans) in vitro and evaluated the anti-caries efficacy of TAX in vivo.

Design: The anti-microbial and anti-biofilm properties of TAX were examined on the S.

Effects of Supplementation With Different Specificities of Dietary Fiber on Health-Related Indicators in Adults With Overweight or Obesity: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Context: Dietary fiber (DF) exhibits variations in its chemical and physical complexity, as well as in its utilization by the gut microbiota. However, the impact of these differences on the health status of adults with overweight or obesity remains unclear.

Objective: This meta-analysis aimed to explore the varying effects of supplementing with different specificities of DF on the health of adults with overweight or obesity, providing guidance on selecting DF supplementation to improve health status.

CircCCT2/miR-146a-5p/IRAK1 axis promotes the development of head and neck squamous cell carcinoma.

Background: Head and neck squamous cell carcinoma (HNSCC), a highly invasive malignancy with a poor prognosis, is one of the most common cancers globally. Circular RNAs (circRNAs) have become key regulators of human malignancies, but further studies are necessary to fully understand their functions and possible causes in HNSCC.

Methods: CircCCT2 expression levels in HNSCC tissues and cells were measured via qPCR.

Synergistic oxidative modification and covalent cross-linking for the construction of sesbania gum-based high efficiency dust suppression foam sols.

To effectively utilize sesbania gum in coal dust control and address the limitations of excessive viscosity and mediocre strength, oxidation treatment was used to improve its fluidity. Polyvinyl alcohol (PVA) and sodium trimetaphosphite (STMP) were used to enhance oxidized sesbania gum OSG, and crosslinking technology was used to improve its mechanical stability. This study developed a novel foam dust suppressant OSG-PVA/SDBS by response surface design, and the optimized dust suppressant material exhibited excellent adhesion and curing properties.

Targeting WDR5/ATAD2 signaling by the CK2/Ikaros axis demonstrates therapeutic efficacy in T-ALL.

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with a poor prognosis and limited options for targeted therapies. Identifying new molecular targets to develop novel therapeutic strategies is the pressing immediate issue in T-ALL. Here, we observed high expression of WD Repeat-Containing Protein 5 (WDR5) in T-ALL; with in vitro and in vivo models we demonstrated the oncogenic role of WDR5 in T-ALL by activating cell cycle signaling through its new downstream effector, ATPase family AAA domain-containing 2 (ATAD2).

A cryo-shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects.

Recovery from spinal cord injury (SCI) is often impeded by neuroinflammation, scar formation, and limited axonal regeneration. To tackle these issues, we developed an innovative biomimetic drug delivery system using liquid nitrogen-treated M2 macrophages (LNT M2) which internalized paclitaxel (PTX) nanoparticles beforehand. These were incorporated into a gelatin methacryloyl (GelMA) scaffold, creating a multifunctional, injectable treatment for single-dose administration.

Enhancing visible light degradation of gaseous formaldehyde with CuO/OVs-TiO photocatalyst loaded wallpaper: Preparation, efficacy and mechanism.

Photocatalytic oxidation is considered to be a highly promising technology for indoor formaldehyde (HCHO) abatement. However, powdered photocatalysts encounter practical challenges due to their recycling difficulties and propensity for aggregation. In this study, we developed a CuO/OVs-TiO photocatalyst dispersion using various physical and chemical methods, which could be stabilized for an extended period.

Comparison of microplastics heteroaggregation with MoS and graphene oxide nanosheets: Dependence on the configuration and impacts on aquatic transport.

Understanding the behavior and fate of microplastics (MPs) in aquatic environment is crucial for assessing their potential risks. This study investigated the heteroaggregation behaviors of MPs with representative 2D nanosheets, MoS and graphene oxide (GO), under various conditions, focusing on the transport behavior of the resulting aggregates. It was found that the destabilization capabilities of 2D nanosheets are notably stronger than those of well-reported nanoparticles.