Publications by authors named "Qendresa Arifi"
Cancer Metastasis Rev
December 2022
Article Synopsis
- - The cancer microenvironment poses a significant barrier to the effectiveness of anticancer treatments, prompting a need for strategies to enhance drug penetration in tumors.
- - Traditional methods like small molecule inhibitors have been ineffective due to increased toxicity and disease progression, while photodynamic therapy (PDT) shows promise by selectively generating reactive oxygen species that improve drug delivery without promoting metastasis.
- - This review explores how PDT alters the cancer microenvironment—by degrading extracellular matrix proteins and inhibiting cancer cell movement—while also identifying gaps in understanding key signaling pathways and the impact of PDT dosing on treatment outcomes.
