Publications by authors named "Qazi Shamima Akhter"

Introduction Contact with the dust of cement consisting of toxic components brings about inflammatory damage (often irreversible) to the body of a human being. The circulatory system exhibits sensitivity to inflammatory changes in the body, and one of the earliest changes may be observed in the blood parameters like mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). MCHC and MCH are possibly easily accessible and affordable parameters that can detect harmful changes in the body before any irreversible damage occurs.

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Article Synopsis
  • Cement dust exposure during manufacturing contains harmful components that can lead to inflammation and changes in blood parameters, specifically red blood cell distribution width (RDW) and mean corpuscular volume (MCV).
  • A study conducted in Dhaka, Bangladesh with 92 participants found that those exposed to cement dust had significantly higher RDW and MCV values compared to those not exposed.
  • The results indicate that cement dust exposure results in notable changes in blood parameters, potentially indicating inflammation-related hemolysis in affected individuals.
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  • Some Bangladeshi adults have lower levels of serum 25(OH)D despite adequate sun exposure and diet, potentially influenced by their genetic makeup, particularly the CYP2R1 gene variant rs10741657.
  • This study analyzed the frequency of this gene variant in a small group of individuals with low (30) and sufficient (10) serum 25(OH)D levels, using various genetic and statistical methods.
  • Findings indicated that the 'GG' and 'GA' genotypes of rs10741657 are significantly linked to low serum 25(OH)D levels among the population studied.
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Background: Prolonged, repeated exposure to cement dust, depending on duration and sensitivity of cement dust-exposed workers, may cause deteriorating effects on the skin, eye, respiratory and hematological system. Toxic cement dust causes inflammatory damage to different body organs. White blood cells (WBCs) are considered cellular markers of ongoing tissue inflammation.

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