Middle Meningeal Artery Embolization for Nonacute Subdural Hematoma.

Background: The effect of embolization of the middle meningeal artery in patients with subacute or chronic subdural hematoma is uncertain.

Methods: We performed a multicenter, open-label, randomized trial in China, involving patients with symptomatic nonacute subdural hematoma with mass effect. Patients were assigned to undergo burr-hole drainage or receive nonsurgical treatment at the surgeon's discretion, and patients in each group were then randomly assigned, in a 1:1 ratio, to undergo middle meningeal artery embolization with liquid embolic material or to receive usual care.

Retraction Note: Study on the functions and mechanism of immune functions of human telomerase reverse transcriptase regulating dendritic cells treating sepsis.

The article "Study on the functions and mechanism of immune functions of human telomerase reverse transcriptase regulating dendritic cells treating sepsis", by H.-M. Chen, L.

A compact multi-pixel superconducting nanowire single-photon detector array supporting gigabit space-to-ground communications.

Classical and quantum space-to-ground communications necessitate highly sensitive receivers capable of extracting information from modulated photons to extend the communication distance from near-earth orbits to deep space explorations. To achieve gigabit data rates while mitigating strong background noise photons and beam drift in a highly attenuated free-space channel, a comprehensive design of a multi-functional detector is indispensable. In this study, we present an innovative compact multi-pixel superconducting nanowire single-photon detector array that integrates near-unity detection efficiency (91.

Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion.

Background: The effects of the glycoprotein IIb/IIIa receptor inhibitor tirofiban in patients with acute ischemic stroke but who have no evidence of complete occlusion of large or medium-sized vessels have not been extensively studied.

Methods: In a multicenter trial in China, we enrolled patients with ischemic stroke without occlusion of large or medium-sized vessels and with a National Institutes of Health Stroke Scale score of 5 or more and at least one moderately to severely weak limb. Eligible patients had any of four clinical presentations: ineligible for thrombolysis or thrombectomy and within 24 hours after the patient was last known to be well; progression of stroke symptoms 24 to 96 hours after onset; early neurologic deterioration after thrombolysis; or thrombolysis with no improvement at 4 to 24 hours.

The Role of Elastase in Corneal Epithelial Barrier Dysfunction Caused by Pseudomonas aeruginosa Exoproteins.

Purpose: To investigate the role of elastase in corneal epithelial barrier dysfunction caused by the exoproteins secreted by Pseudomonas aeruginosa.

Methods: Exoproteins obtained from Pseudomonas aeruginosa culture supernatant were analyzed by shotgun proteomics approach. In vitro multilayered rabbit corneal epithelial barrier model prepared by air-liquid interface technique (CECs-ALI) were treated with 2 µg/ml exoproteins and/or 8 mM elastase inhibitor.

Excited state structural dynamics of tetra(4-aminophenyl)porphine in the condensed phase: resonance Raman spectroscopy and density functional theory calculation study.

Resonance Raman spectra (RRs) of tetra(4-aminophenyl) porphine (TAPP) were obtained, and density functional calculations were done to help the elucidation of the photorelaxation dynamics of Soret (B(x) and B(y) band) and Q(y) electronic transitions. The RRs indicate that the photorelaxation dynamics for the S(0) --> S(3) excited electronic state is predominantly along the totally symmetric porphin ring C(beta)=C(beta) + C(m)C(alpha) stretch, C(m)-ph stretch, and simultaneously along the asymmetric nu(C(m)C(alpha))(as) and nu(C(alpha)C(beta))(as) relaxation processes leading to Q(y) while that for S(0) --> S(2) is predominantly along the porphin ring C(beta)=C(beta) + C(m)C(alpha) stretch and simultaneously along the asymmetric nu(C(m)C(alpha))(as) + nu(C(alpha)C(beta))(as) relaxation processes leading to thermal equilibrium in Q(x). The excited state structural dynamics of TAPP determined from RRs shows that internal conversion B(x) --> Q(y) electronic relaxation occurs in tens of femtoseconds and the short-time dynamics were first interpreted with account of the time-dependent wave packet theory and Herzberg-Teller contributions.