ACS Appl Mater Interfaces
October 2024
Single-phase BaMSiO (M = Yb, Er, Y, Ho) ceramics have been investigated for their crystal structures, microwave dielectric properties, flexural strength, and potential applications in dielectric antennas. Rietveld refinement and TEM analysis revealed that the BaMSiO ceramics exhibit a monoclinic structure (space groups: 2/). The ε of the BaMSiO ceramics was dominated by ionic polarizability and ρ.
View Article and Find Full Text PDFCa-substituted BaCaMgAlSiO ceramics were prepared to explore the relationships among their crystal structural parameters, phase compositions, dielectric properties, and coefficients of thermal expansion and applications in C-band antenna. The maximum solubility of BaCaMgAlSiO was located at = 0.25, and BaCaMgAlSiO ceramics (0 ≤ ≤ 0.
View Article and Find Full Text PDFAdrenocortical carcinoma (ACC) is a rare, heterogeneous, and aggressive malignancy with a generally poor prognosis. Surgical resection is the optimal treatment plan. After surgery, both mitotane treatment or the etoposide-doxorubicin-cisplatin (EDP) protocol plus mitotane chemotherapy have a certain effect, but there is still an extremely high possibility of recurrence and metastasis.
View Article and Find Full Text PDFBackground: Two risk variants in the apolipoprotein L1 gene ( ) have been associated with increased susceptibility to sepsis in Black patients. However, it remains unclear whether high-risk genotypes are associated with occurrence of either sepsis or sepsis-related phenotypes in patients hospitalized with infections, independent of their association with pre-existing severe renal disease.
Methods: A retrospective cohort study of 2,242 Black patients hospitalized with infections.
is a famous living fossil that plays a significant role in the evolutionary studies of the plant kingdom. To explore the adaptive evolution of the ancient genus Isoetes from China, we focused on (Q.F.
View Article and Find Full Text PDFBackground: Thiopurines are an important class of immunosuppressants despite their risk for hematopoietic toxicity and narrow therapeutic indices. Benign neutropenia related to an variant (rs2814778-CC) is common among persons of African ancestries.
Objective: To test whether rs2814778-CC was associated with azathioprine discontinuation attributed to hematopoietic toxicity and lower thiopurine dosing.
Background: Lp(a) (lipoprotein [a]) levels are higher in individuals of African ancestry (AA) than in individuals of European ancestry (EA). We examined associations of genetically predicted Lp(a) levels with (1) atherosclerotic cardiovascular disease subtypes: coronary heart disease, cerebrovascular disease, peripheral artery disease, and abdominal aortic aneurysm and (2) nonatherosclerotic cardiovascular disease phenotypes, stratified by ancestry.
Methods: We performed (1) Mendelian randomization analyses for previously reported cardiovascular associations and (2) Mendelian randomization-phenome-wide association analyses for novel associations.
In this study, a novel, oxidized poly (arylene sulfide sulfone) (O-PASS) nanofibrous membrane filter was successfully fabricated for the effective removal of particulate matter. PASS was electrospun into a nanofibrous membrane with an average nanofiber diameter of 0.31 µm and basis weight of 3 g/m.
View Article and Find Full Text PDFMajor adverse cardiovascular events are closely associated with 24-hour blood pressure (BP). We determined outcome-driven thresholds for 24-hour mean arterial pressure (MAP), a BP index estimated by oscillometric devices. We assessed the association of major adverse cardiovascular events with 24-hour MAP, systolic BP (SBP), and diastolic BP (DBP) in a population-based cohort (n=11 596).
View Article and Find Full Text PDFBackground: Masked hypertension is associated with adverse cardiovascular outcomes. Nonetheless, no randomized controlled trials exist in the treatment of masked hypertension. The aim of this randomized, placebo-controlled trial was to investigate the efficacy and safety of blood pressure (BP)-lowering treatment with a Chinese herbal formula, gastrodia-uncaria granules, in patients with masked hypertension.
View Article and Find Full Text PDFUnderstanding the dynamics of primary productivity in a rapidly changing marine environment requires mechanistic insight into the photosynthetic processes (light absorption characteristics and electron transport) in response to the variability of environmental conditions and algal species. Here, we examined the photosynthetic performance and related physiological and ecological responses to oceanic properties [temperature, salinity, light, size-fractionated chlorophyll (Chl ) and nutrients] and phytoplankton communities in the oligotrophic Western Pacific Ocean (WPO). Our results revealed high variability in the maximum (F/F; 0.
View Article and Find Full Text PDFPulsatile blood pressure (BP) confers cardiovascular risk. Whether associations of cardiovascular end points are tighter for central systolic BP (cSBP) than peripheral systolic BP (pSBP) or central pulse pressure (cPP) than peripheral pulse pressure (pPP) is uncertain. Among 5608 participants (54.
View Article and Find Full Text PDFParticipant-level meta-analyses assessed the age-specific relevance of office blood pressure to cardiovascular complications, but this information is lacking for out-of-office blood pressure. At baseline, daytime ambulatory (n=12 624) or home (n=5297) blood pressure were measured in 17 921 participants (51.3% women; mean age, 54.
View Article and Find Full Text PDFBackground: Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to explore the potential side effects and repurposing potential of antihypertensive drugs, which are among the most commonly used medications worldwide.
Methods: Genetic proxies for the effect of antihypertensive drug classes were identified as variants in the genes for the corresponding targets that associated with systolic blood pressure at genome-wide significance.
To explore the toxicity and action mechanism of acute sulfur dioxide (SO) on urban landscape plants, a simulated SO stress environment by using fumigation chamber involving increasing SO concentration (0, 25, 50, 100, 200 mg m) was carried out among three species. After 72 h of exposure, SO-induced oxidative damage indicated by electrolyte leakage increased with higher dose of SO. Meanwhile, SO decreased the contents of chlorophyll a, chlorophyll b and carotenoid and increased the contents of sulfur.
View Article and Find Full Text PDFBackground: Coronary heart disease (CHD) is a leading cause of death globally. Although therapy with statins decreases circulating levels of low-density lipoprotein cholesterol and the incidence of CHD, additional events occur despite statin therapy in some individuals. The genetic determinants of this residual cardiovascular risk remain unknown.
View Article and Find Full Text PDFThis article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
View Article and Find Full Text PDFNo previous study has addressed the relative contributions of environmental and genetic cues to the diurnal blood pressure rhythmicity. From 24-hour ambulatory recordings of systolic blood pressure obtained in untreated patients (51% women; mean age, 51 years), we computed the night-to-day ratio in 897 and morning surge in 637. Environmental cues included season, mean daily outdoor temperature, atmospheric pressure, humidity and weekday, and the genetic cues 14 single nucleotide polymorphisms in 10 clock genes.
View Article and Find Full Text PDFNo previous population study assessed sublingual capillary density (CD) or perfused boundary region (PBR). Lower PBR indicates greater glycocalyx width. In 252 Han and 220 She Chinese and 254 Flemish people (mean age, 51.
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