Publications by authors named "Q Y Zhang"
Named after the Greek term for "hard fat", stearic acid has gradually entered people's field of vision. As an important component of various physiological cellular functions, stearic acid plays a regulatory role in diverse aspects of energy metabolism and signal transduction. Its applications range from serving as a bodily energy source to participating in endogenous biosynthesis.
View Article and Find Full Text PDFBackground: Ultrasound training is crucial for residents across specialties but presents challenges for residents that are not specializing in ultrasound. Investigating the effectiveness of competency-based ultrasound curricula for a wider range of medical specialties is imperative.
Methods: A total of 250 residents who attended the ultrasound curriculum between June 2023 and June 2024 were included in the analysis.
Article Synopsis
- This study aimed to explore the link between glycemic control and lung health using data from 5,610 participants in the NHANES survey from 2007-2012, focusing on respiratory symptoms and lung function tests.
- Results indicated that a 1% increase in blood glucose was negatively correlated with lung function, leading to reduced forced expiratory volume (FEV1) and forced vital capacity (FVC), along with a higher risk of breathing difficulties and mortality for those with restrictive lung disease.
- Improved glycemic control was associated with early markers of lung damage, whereas poor control correlated with more severe lung dysfunction, emphasizing the importance of managing blood glucose levels for respiratory health.
This study aimed to evaluate the impact of apatinib (APT) mesylate on the growth, migration ability, and underlying mechanisms in esophageal squamous cell carcinoma (ESCC) cell lines Kyse30 and Kyse150. Additionally, the anti-metastatic effects of APT mesylate were further validated in a nude mouse xenograft metastasis model. In vitro, APT mesylate treatment significantly reduced cell viability and migration ability in both cell lines in a dose- and time-dependent manner.
View Article and Find Full Text PDFSoluble cytotoxic oligomers produced during the fibrillation of both α-synuclein (αS) and amyloid-β protein (Aβ) are key pathogenic factors in Parkinson's disease (PD) and Alzheimer's disease (AD). Reducing toxic oligomers by regulating the aggregation process of αS and Aβ is an important strategy for the treatment of PD and AD. Herein, tetrahydrofolic acid (THF) is found to accelerate amyloid fibrillization, decreases cytotoxic oligomers and suppresses their toxicity.
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