Reference Values of Handgrip and Lower Extremity Strength for Vietnamese Men and Women: The Vietnam Osteoporosis Study.

Background: Falls and sarcopenia are significant public health issues in Vietnam. Despite muscle strength being a critical predictor for these conditions, reference data on muscle strength within the Vietnamese population are lacking.

Purpose: To establish the reference ranges for muscle strength among Vietnamese individuals.

A STAT3-STING-IFN axis controls the metastatic spread of small cell lung cancer.

Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor characterized by a high metastatic potential with an overall survival rate of ~5%. The transcription factor signal transducer and activator of transcription 3 (STAT3) is overexpressed by >50% of tumors, including SCLC, but its role in SCLC development and metastasis is unclear. Here, we show that, while STAT3 deletion restricts primary tumor growth, it paradoxically enhances metastatic spread by promoting immune evasion.

Amelioration of Cancer Cachexia by Extract Through AKT Signaling Pathway Regulation.

Cancer cachexia is a multifactorial syndrome characterized by the progressive loss of skeletal muscle mass and adipose tissue. is widely used in traditional medicine in Korea and China to treat various diseases. However, its exact role and underlying mechanism in regulating cancer cachexia have not been elucidated yet.

Relationship between water quality and phytoplankton distribution of aquaculture areas in a tropical lagoon.

Aquaculture activities can affect water quality and phytoplankton composition. Our study estimated phytoplankton density and composition relating to aquaculture-impacted environmental factors. We analyzed water quality and phytoplankton at 35 sites in a tropical brackish lagoon, including inside aquaculture ponds (integrated farming of fish, shrimp, and crab), at wastewater discharge points, within 300 m of these points, and farther out in the lagoon.