Publications by authors named "Q Perrenoud"

Article Synopsis
  • Patients with focal temporal lobe seizures often lose consciousness, showing brain activity similar to deep sleep.
  • Previous studies in rats suggest that reduced arousal in the brain leads to decreased brain function during these seizures, but they didn't connect this to conscious behavior.
  • In this study using awake mice, researchers found that seizures affect behavior, particularly responses to sounds, by altering acetylcholine levels in the brain, highlighting the link between reduced brain activity and loss of consciousness during these episodes.
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Cognitive and behavioral processes are often accompanied by changes within well-defined frequency bands of the local field potential (LFP i.e., the voltage induced by neuronal activity).

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Cognitive and behavioral processes are often accompanied by changes within well-defined frequency bands of the local field potential (LFP i.e., the voltage induced by neuronal activity).

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Visually evoked synchrony in the primary visual cortex has proven to be a robust model for examining circuit interactions. In this issue of Neuron, Veit et al. highlight a previously unappreciated role for VIP interneurons in regulating local and long-range patterns of coordinated neural activity.

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Article Synopsis
  • GABAergic interneurons show similar classifications across brain regions, but their distinction in the hilus of the dentate gyrus is uncertain.
  • Using patch-clamp techniques and single cell RT-PCR, researchers found that common electrophysiological and molecular traits effectively classify cortical interneurons, but not those in the hilus.
  • The study suggests that, although traditional molecular markers are still relevant, hilar interneurons do not have distinct electrophysiological features to support separate classifications.
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