α-Latrotoxin (αLTX) causes exhaustive release of neurotransmitters from nerve terminals in the absence of extracellular Ca (Ca). To investigate the mechanisms underlying this effect, we loaded mouse neuromuscular junctions with BAPTA-AM. This membrane-permeable Ca-chelator demonstrates that Ca-independent effects of αLTX require an increase in cytosolic Ca (Ca).
View Article and Find Full Text PDFWe present induced refractive index changes in biocompatible silk fibroin hydrogels using two different femtosecond laser systems: one using 400 nm at 80 MHz and the other employing 517 nm at 8.3 MHz. Both modalities produced significant index changes, demonstrating the potential to create custom refractive correctors.
View Article and Find Full Text PDFIncreased technology adoption has significantly transformed how governments interact with citizens. Today, e-government services and tools are integral to modern public administration. Factors affecting users' adoption of e-government services have been studied in the past.
View Article and Find Full Text PDFBMJ Open
August 2024
Mymensingh Med J
October 2024
Among the different complications of chronic kidney diseases, peripheral arterial disease is not uncommon. Though it is an indicator of widespread atherosclerosis, sometimes it is neglected in CKD patients. Our study was done to evaluate the frequency and pattern of PAD in chronic kidney disease patients admitted in a tertiary care hospital of Bangladesh.
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