Deciphering the impact of dietary habits and behavioral patterns on colorectal cancer.

Colorectal cancer (CRC) is a malignant tumor that originates from the epithelial cells of the colon and rectum. Global epidemiological data shows that in 2020, the incidence and mortality rate of CRC ranked third and second, respectively, posing a serious threat to people's health and lives. The factors influencing CRC are numerous and can be broadly categorized as modifiable and non-modifiable based on whether they can be managed or intervened upon.

Dual active site and metal-substrate interface effect endow platinum-ruthenium/molybdenum carbide efficient pH-universal hydrogen evolution reaction.

Exploring suitable dual active site and metal-substrate interface effect is essential for designing efficient and robust electrocatalysts across a wide pH range for the hydrogen evolution reaction (HER). Herein, alloyed platinum-ruthenium clusters supported on nanosheet-assembled molybdenum carbide microflowers (PtRu/MoC) are reported as efficient pH-universal electrocatalysts for HER. Due to dual active site and metal-substrate interface effect, the optimized PtRu/MoC electrocatalyst exhibits extremely low overpotentials (η) of 9, 19, and 33 mV to deliver 10 mA cm in 0.

Silver Microdisc Array Electrode Chip for Urea Detection in Saliva Samples from Patients with Chronic Nephritis.

Urea is an important biomarker for diagnosing various kidney and liver disorders. However, many existing methods rely on invasive blood sampling, which can potentially harm patients. Saliva has been recently recognized as a noninvasive and easily collectible alternative to blood for urea quantification.

CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding.

Fruit firmness is crucial for storability, making cultivating varieties with higher firmness a key target in tomato breeding. In recent years, tomato varieties primarily rely on hybridizing ripening mutants to produce F hybrids to enhance firmness. However, the undesirable traits introduced by these mutants often lead to a decline in the quality of the varieties.

SERS Detection of Hydrophobic Molecules: Thio-β-Cyclodextrin-Driven Rapid Self-Assembly of Uniform Silver Nanoparticle Monolayers and Analyte Trapping.

High-sensitivity and repeatable detection of hydrophobic molecules through the surface-enhanced Raman scattering (SERS) technique is a tough challenge because of their weak adsorption and non-uniform distribution on SERS substrates. In this research, we present a simple self-assembly protocol for monolayer SERS mediated by 6-deoxy-6-thio-β-cyclodextrin (β-CD-SH). This protocol allows for the rapid assembly of a compact silver nanoparticle (Ag NP) monolayer at the oil/water interface within 40 s, while entrapping analyte molecules within hotspots.