Fluorescence Analysis of Quinine in Commercial Tonic Waters.

Quinine is known for treating malaria, muscle cramps, and, more recently, has been used as an additive in tonic water due to its bitter taste. However, it was shown that excessive consumption of quinine can have severe side effects on health. In this work, we utilized fluorescence spectroscopy to measure the concentration of quinine in commercial tonic water samples.

Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues.

Spatial transcriptomics (ST) offers enormous potential to decipher the biological and pathological heterogeneity in precious archival cancer tissues. Traditionally, these tissues have rarely been used and only examined at a low throughput, most commonly by histopathological staining. ST adds thousands of times as many molecular features to histopathological images, but critical technical issues and limitations require more assessment of how ST performs on fixed archival tissues.

Stress generation and subsequent repetitive negative thinking link poor executive functioning and depression.

Background And Objective: Poor executive functioning (EF) has been consistently linked to depression, but questions remain regarding mechanisms driving this association. The current study tested whether poor EF is linked to depression symptoms six weeks later via dependent stressors (model 1) and stressors perceived to be uncontrollable (model 2) at week two (W2) and repetitive negative thinking (RNT) at W4 during early COVID-19 in college students.

Design: This was a longitudinal study with four timepoints spanning six weeks (April-June 2020).

Basin-Size Mapping: Prediction of Metastable Polymorph Synthesizability Across TaC-TaN Alloys.

The sizes of the basins of attraction on the potential energy surface are helpful indicators in determining the experimental synthesizability of metastable phases. In principle, these basins can be controlled with changes in thermodynamic conditions such as composition, pressure, and surface energy. Herein, we use random structure sampling to computationally study how alloying smoothly perturbs basin of attraction sizes.

Evaluation of Genetic Diversity of Black Soybean [ (L.) Merr] by Using RAPD and ISSR Markers.

<b>Background and Objective:</b> Black soybeans [<i>Glycine max</i> (L.) Merr] are among the important crops, but the cultivated resources are normally low-yielding, susceptible to diseases and low profit. Therefore, it is necessary to evaluate the genetic diversity of black soybean germplasms for breeding programs.