Publications by authors named "Q Ciampi"
Background: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity including patients with different phenotypes of near normal, normal, and supernormal left ventricular (LV) function.
Objectives: To assess the value of resting LV elastance (also known as force) with transthoracic echocardiography (TTE) to identify HFpEF phenotypes.
Methods: In a prospective, observational, multicenter study, 2380 HFpEF patients were recruited from July 2016 to May 2024.
Objective: Atrial cardiomyopathy is closely associated with atrial fibrillation (AF), and some patients exhibit no dysfunction at rest but demonstrate evident changes in left atrial (LA) function and LA volume during exercise. This study aimed to identify distinguishing signs during exercise stress echocardiography (ESE) among patients in sinus rhythm (SR), with and without history of paroxysmal/persistent AF (PAF).
Methods: A prospective cohort of 1055 patients in SR was enrolled across 12 centers.
Hypercontractile phenotype (HP) of the left ventricle (LV) is an actionable therapeutic target in patients with chronic coronary syndromes (CCS) or heart failure (HF), but its clinical recognition remains difficult. To assess the clinical variables associated with the HP. In a prospective, observational, multicenter study, we recruited 5122 patients (age 65 ± 11 years, 2974 males, 58%) with CCS and/or HF with preserved ejection fraction (EF).
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- Regional wall motion abnormalities (RWMA) can be absent during stress echocardiography in patients with chronic coronary syndromes, even when coronary flow velocity reserve (CFVR) indicates significant disease.
- A study involving 749 patients showed that those with inducible RWMA had lower CFVR and that 69% underwent coronary revascularization, with 10-year survival rates significantly better in those treated invasively versus conservatively.
- The findings suggest a physiology-driven approach based on CFVR may be valuable for coronary revascularization decisions in patients with significant left anterior descending coronary artery disease.
Article Synopsis
- * A survey of 159 centers showed that over 30% of echocardiography workloads are related to cancer, with most centers primarily using TTE to assess left ventricular ejection fraction (LVEF). However, many are still using outdated methods for these assessments.
- * The findings indicate a significant gap between current practices and recommended standards, highlighting the need for better collaboration between cardiologists and oncologists to improve cancer patient care and establish dedicated cardio-oncology services.