Publications by authors named "Pyung-Goo Cho"

Background: Population-based studies on the cause of readmission within 90 days after surgery or radiotherapy for metastatic spine tumors are scarce. We aimed to investigate the risk factors for readmission within 90 days after initial surgical or radiation treatment for metastatic spine tumors.

Methods: Patients who were diagnosed with metastatic spine tumors between 2012 and 2019 and underwent spinal magnetic resonance imaging within 1 year were classified according to treatment (surgical or radiotherapy groups), and the causes of the 90-day readmission and patient characteristics were compared.

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  • A study evaluated an automatic landmark detection model using 1017 lateral whole-spine radiographs collected between January 2020 and December 2021, splitting the data into training (819 images) and testing (198 images) sets, with additional external validation using 690 images from other institutions.
  • The model showed the best accuracy in detecting cervical landmarks (error of 1.5-2.4 mm), followed by lumbosacral landmarks (error of 2.1-3.0 mm), while thoracic landmarks had larger errors (2.4-4.3 mm).
  • The model's performance was highly reliable, with excellent agreement between the AI and expert measurements, evidenced by an intraclass correlation coefficient above
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Traumatic spinal cord injury (TSCI) has significant physical, psychological, and socioeconomic impacts. However, the epidemiological characteristics and treatment patterns of TSCI in South Korea remain unclear. This study aimed to investigate TSCI incidence and treatment behaviors in South Korea from 2008 to 2020.

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Objective: Precise knowledge regarding the mechanical stress applied to the intervertebral disc following each individual spine motion enables physicians and patients to understand how people with discogenic back pain should be guided in their exercises and which spine motions to specifically avoid. We created an intervertebral disc degeneration model and conducted a finite element (FE) analysis of loaded stresses following each spinal posture or motion.

Methods: A 3-dimensional FE model of intervertebral disc degeneration at L4-5 was constructed.

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: Evogliptin tartrate inhibits dipeptidyl peptidase-4 (DPP-4), boosting glucagon-like peptide 1 (GLP-1) secretion and improving insulin release and glucose tolerance, while also exerting anti-inflammatory effects. We investigated its anti-inflammatory and analgesic effects. : Forty male Sprague Dawley rats were divided into (N = 10 in each): (1) naïve, (2) complete Freund's adjuvant (CFA) inflammation + evogliptin tartrate (once for 10 mg/kg) (CFAE), (3) CFA + vehicle (same volume with normal saline with evogliptin tartrate/once) (CFAV), and (4) CFA + indomethacin (5 mg/mL/kg/1 time) (CFAI) groups.

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  • Osteoporosis increases the risk of fractures, leading to serious health issues and decreased quality of life, making it crucial to prevent further fractures, particularly the secondary osteoporotic vertebral compression fractures (OVCFs).
  • The study analyzed 178 patients who experienced their first OVCF, focusing on demographics, bone mineral density, and pelvic parameters to identify risk factors for a second OVCF.
  • Results showed that 38.2% of patients experienced a second OVCF, with lower bone mineral density and a less favorable muscle-to-fat ratio increasing the likelihood, while injection medications were more effective in reducing risk compared to oral medications.
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Pancreatic cancer is an aggressive malignant cancer that shows the lowest survival rates. Recently, the 5-year survival rate of pancreatic cancer has been increasing, owing to early diagnosis and therapeutic advancement. The purpose of this study was to investigate the clinical characteristics and significant prognostic factors of spinal metastatic pancreatic cancer.

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Objective: To determine the effectiveness of the unsubtracted roadmap technique (USRT) for decreasing cement leakage (CL) during percutaneous vertebroplasty (PVP).

Methods: In this retrospective cohort study, patients who underwent PVP between January and November 2018 were included. Patients were divided into the unsubtracted roadmap (UR) (n = 20) and conventional venography (CV) (n = 22) groups.

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  • - The study investigated the value of immediate postoperative MRI in 172 patients after lumbar microdiscectomy, assessing its correlation with postoperative pain, despite previous research showing MRI results are often similar to preoperative scans.
  • - Out of the patients, 29 showed complications like dural sac compression on their post-surgery MRIs, but only 10 of these patients experienced pain, while 19 did not; conversely, 38 out of 143 without complications still reported pain.
  • - The research concluded that intraoperative blood loss and the Charlson comorbidity index (CCI) are significant factors predicting postoperative pain, regardless of MRI findings, indicating these may be more critical in understanding patient outcomes.
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Artificial intelligence (AI) is a field of computer science that equips machines with human-like intelligence and enables them to learn, reason, and solve problems when presented with data in various formats. Neurosurgery is often at the forefront of innovative and disruptive technologies, which have similarly altered the course of acute and chronic diseases. In diagnostic imaging, such as X-rays, computed tomography, and magnetic resonance imaging, AI is used to analyze images.

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  • A meta-analysis was conducted to identify risk factors for unplanned readmission after anterior cervical discectomy and fusion (ACDF) surgery, which is important due to rising healthcare costs and quality management concerns.
  • The analysis included 10 studies from multiple databases, examining various demographic and health-related factors that contribute to unplanned readmissions.
  • Significant risk factors identified include older age, male gender, pre-existing conditions like hypertension, diabetes, and coronary artery disease, a higher ASA physical status grade, anxiety, depression, and perioperative pulmonary complications.
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Purpose: Giant cell tumors (GCTs) are common benign primary bone tumors and are well known for their locally aggressive performance and tendency to recur. The purpose of this study was to analyze the effects of denosumab and risk factors for recurrent spinal GCTs.

Materials And Methods: We searched PubMed, EMBASE, Web of Science, and Cochrane Library databases to identify differences between individuals treated with and without denosumab and risk factors for spinal GCT recurrence.

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Degenerative lumbar spine disease is becoming increasingly prevalent in the aging population. Surgical treatment is the standard treatment modality for intractable cases, but the reoperation rate remains high. We conducted this study to longitudinally evaluate the impact of health risk factors on the risk of lumbar spine reoperation in Koreans aged over 40 years.

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Purpose: The 5-year postoperative failure rate of conventional shunt treatment for syringomyelia is 50%, with arachnoditis, shunt obstruction, and shunt malfunction being the most common causes. We report a new syringo-cisterna magna (SCM) shunt that allows syrinx cerebrospinal fluid (CSF) drainage normally into the cerebellomedullary cisterns through the subarachnoid space.

Methods: Between November 2012 and February 2017, six patients (mean age: 57.

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This study investigated risk factors for 30-day readmission of discharged patients who had undergone lumbar spinal surgery. This retrospective, case-control study reviewed 3,933 patients discharged after elective spinal surgery for lumbar degenerative diseases from 2005 to 2012 at a university hospital. Of these patients, 102 were re-hospitalized within 30 days of discharge.

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  • A cervicogenic headache (CEH) can be tricky to diagnose because it has different causes; this study explored the effectiveness of SPECT/CT imaging for diagnosing CEH and guiding treatment.
  • In a study with 23 CEH patients, those who underwent SPECT/CT imaging received specific injections based on their results, while a control group received a different type of treatment.
  • Six months later, patients treated based on SPECT/CT findings showed significantly better outcomes in pain and disability scores compared to the control group, suggesting that SPECT/CT is useful for accurately targeting treatment.
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Objective: Lumbar discectomy is an effective treatment for lumbar disc herniation (LDH); however, up to 2-18% of patients with LDH have experienced recurrent disc herniation. The purpose of this study was to evaluate the efficacy of a novel annular closure device (ACD) for preventing LDH recurrence and re-operation compared with that of conventional lumbar discectomy (CLD).

Methods: In this prospective randomized controlled trial, we compared CLD with discectomy utilizing the Barricaid® (Intrinsic Therapeutics, Inc.

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Objective: To determine whether the outcomes of percutaneous epidural neuroplasty (PEN) are influenced by the type of lumbar disc herniation (LDH) and evaluate the effectiveness of PEN in patients with single-level LDH.

Methods: This study included 430 consecutive patients with single-level LDH who underwent PEN. Before treatment, the LDH type was categorized as bulging, protrusion, extrusion, and sequestration, while Pfirrmann grades were assigned according to imaging findings.

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Background Context: Posterolateral fusion (PLF) with autogenous iliac bone graft is one of the most common surgical procedures for lumbar spinal disease. However, its limited success demands new biologically competent graft enhancers or substitutes. Although the use of direct current (DC) electrical stimulation has been shown to increase rate of successful spinal fusions, little is known about the effect of the type of current in DC stimulation.

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Study Design: In-vitro biomechanical investigation.

Purpose: To evaluate the biomechanical effects of the degeneration of the biodegradable cervical plates developed for anterior cervical discectomy and fusion (ACDF) on fusion and adjacent levels.

Overview Of Literature: Biodegradable implants have been recently introduced for cervical spine surgery.

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To investigate factors associated with surgical outcomes of cervical ossification of the posterior longitudinal ligament (OPLL). This retrospective study included patients (662 males and 251 females; mean age 55.8 years) with symptomatic OPLL.

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Background: The correlation between epidurography contrast patterns and the clinical outcomes of percutaneous epidural neuroplasty (PEN) remains unclear.

Objective: To analyze the correlation between postadhesiolysis epidurography contrast patterns and the clinical outcomes of patients who undergo lumbar PEN.

Design: This study is a retrospective analysis of 78 consecutive patients who underwent lumbar PEN between April 2012 and March 2013.

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We report a case of a solitary osteochondroma as a dumbbell tumor compressing the spinal cord and its surgical strategy. The patient is a 16-year-old female with longstanding posterior neck pain and left arm abduction weakness. She was examined by plain X-ray, three-dimensional-computed tomography, magnetic resonance imaging, and vertebral angiography.

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Background: Cervical disc disease is a common and occasionally disabling condition, occurring as a natural consequence of aging in the vast majority of the adult population. Percutaneous epidural neuroplasty (PEN) has been used to deliver highly concentrated drugs for chronic neck pain and to prevent scarring in cases refractory to conventional epidural blocks. However, the clinical course after PEN in cervical disc disease is not well-documented.

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Purpose: Our purpose was to evaluate the efficacy of teriparatide for posterior lumbar interbody fusion (PLIF) in osteoporotic women.

Methods: Forty-seven osteoporotic patients underwent PLIF with pedicle screw fixation for degenerative lumbar stenosis and instability. Patients were divided into two groups.

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