Surge of severe acute respiratory syndrome coronavirus 2 infections linked to single introduction of a virus strain in Myanmar, 2020.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a major health concern globally. Genomic epidemiology is an important tool to assess the pandemic of coronavirus disease 2019 (COVID-19). Several mutations have been reported by genome analysis of the SARS-CoV-2.

Prevalence of Extended-Spectrum Beta-Lactamase/Carbapenemase Genes and Quinolone-Resistance Determinants in Clinical Isolates from Respiratory Infections in Myanmar.

In recent years, nosocomial infections due to multidrug resistant strains have been increasing, associated with growing trend of resistance to beta-lactams and fluoroquinolones (FQs) worldwide. In this study, prevalence of beta-lactamase genes and resistance mechanisms to FQ were analyzed in 191 clinical isolates derived from respiratory tract infections in a teaching hospital in Yangon, Myanmar. The major extended-spectrum beta-lactamase gene was , which was detected in 33% of isolates, with CTX-M-15 being dominant.

Genetic Diversity of CMY Beta-Lactamase Genes in Clinical Isolates of in Myanmar: Identification of Three Novel Types and Updated Phylogenetic Classification of .

The dissemination of CMY-type enzymes, one of the plasmid-mediated AmpC beta-lactamases, among Enterobacteriaceae has become an important public health concern. In this study, genetic diversity of CMY beta-lactamase genes was investigated for 50 -positive isolates detected from 426 clinical isolates of in Yangon, Myanmar. CMY genes were differentiated into 9 types, with being predominant (22 isolates, 44%), followed by , , , and included three novel types (CMY-156, CMY-158, CMY-159).

Molecular Characterization of Methicillin-Susceptible and -Resistant Harboring Panton-Valentine Leukocidin-Encoding Bacteriophages in a Tertiary Care Hospital in Myanmar.

Panton-Valentine leukocidin (PVL) is a pore-forming toxin encoded by genes on bacteriophages distributed to , associated with its increased virulence to humans. In this study, molecular epidemiological characteristics were investigated for 239 clinical isolates of collected in a tertiary care hospital in Yangon, Myanmar, particularly with regard to methicillin resistance and PVL genes. Methicillin-resistant (MRSA) accounted for 13.