Publications by authors named "Puxiang Zhen"
Article Synopsis
- * Using Mendelian randomization, a method that helps establish causal relationships, the study investigated whether high lipid levels are a risk factor for RCS and if lipid-lowering medications are effective in its treatment.
- * The results did not find a direct causal relationship between lipid levels and RCS; however, inhibiting HMG-CoA reductase (HMGCR) was associated with a reduced risk of RCS, indicating some connection that warrants further exploration.
Background: Tibial Cortex Transverse Transport (TTT) represents an innovative surgical method for treating lower extremity diabetic foot ulcers (DFUs), yet its underlying mechanisms remain elusive. Establishing an animal model that closely mirrors clinical scenarios is both critical and novel for elucidating the mechanisms of TTT.
Methods: We established a diabetic rat model with induced hindlimb ischemia to mimic the clinical manifestation of DFUs.
Background: The management of severe and recalcitrant diabetic foot ulcers is challenging. Distraction osteogenesis is accompanied by vascularization and regeneration of the surrounding tissues. Longitudinal distraction of the proximal tibia stimulates increased and prolonged blood flow to the distal tibia.
View Article and Find Full Text PDF[The effectiveness of Ilizarov technique-based transverse tibial bone transport on treatment of severe diabetic foots complicated with systemic inflammation response syndrome].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
October 2018
Objective: To evaluate the effectiveness of Ilizarov technique-based transverse tibial bone transport on the treatment of severe diabetic foot ulcer (Wagner grades 3 to 5) complicated with systemic inflammatory response syndrome (SIRS).
Methods: Between August 2014 and December 2017, 33 patients with severe diabetic foot and SIRS were treated with Ilizarov technique-based transverse tibial bone transport. There were 27 males and 6 females, with a mean age of 60.