Publications by authors named "Putri Nur Fatin"
NPJ Breast Cancer
July 2024
Article Synopsis
- Triple-negative breast cancers (TNBCs) are challenging to treat, but some may respond to PARP inhibitors based on their genetic features, even if they don't carry BRCA mutations.
- Researchers analyzed genomic data from 129 TNBC samples in Malaysia, creating a machine learning tool to identify homologous recombination deficiency (HRD) in these cancers.
- The classifier showed high accuracy in detecting HRD features, which could help identify TNBC patients who might benefit from specific treatments like PARP inhibitors or platinum-based chemotherapy.
