From the depths of the Java Trench: genomic analysis of Priestia flexa JT4 reveals bioprospecting and lycopene production potential.

Background: The marine environment boasts distinctive physical, chemical, and biological characteristics. While numerous studies have delved into the microbial ecology and biological potential of the marine environment, exploration of genetically encoded, deep-sea sourced secondary metabolites remains scarce. This study endeavors to investigate marine bioproducts derived from deep-sea water samples at a depth of 1,000 m in the Java Trench, Indonesia, utilizing both culture-dependent and whole-genome sequencing methods.

Selection of optimal knot point and best geographic weighted on geographically weighted spline nonparametric regression model.

This study proposes the development of a nonparametric regression model combined with geographically weighted regression. The regression model considers geographical factors and has a data pattern that does not follow a parametric form to overcome the problem of spatial heterogeneity and unknown regression functions. This study aims to model provincial food security index data in Indonesia with the GWSNR model, so finding the optimal knot point and the best geographic weighting is necessary.

A Case of Superficial Siderosis with Elevated Anti-Ro/SSA Antibody.

Superficial siderosis (SS) of the central nervous system is a rare disorder that is caused by chronic or recurrent hemorrhage in the subarachnoid space via a dural defect at the spinal level. The most common clinical features of SS include slow-progressive sensorineural deafness, cerebellar symptoms, and pyramidal tract signs. Considering that SS can present with broad clinical manifestations, for precise diagnosis, this disease must be understood.

Effect of cogon grass root ethanol extract on fatty acid binding protein 4 and oxidative stress markers in a sepsis mouse model.

Sepsis causes several immunological and metabolic alterations that induce oxidative stress. The modulation of fatty acid-binding protein 4 (FABP4) has been shown to worsen this condition. Extract of cogon grass root (ECGR) contains flavonoids and isoeugenol compounds that exhibit anti-inflammatory and antioxidant properties.

(haramonting) protects against allethrin-exposed pulmo damage in rats: mechanistic interleukins.

Inhaling Allethrin (C19H26O3) may induce oxidative stress in lung cells by causing the formation of free radi-cals. Interleukins (IL) are a group of secreted cytokines or proteins and signaling molecules initially produced as an immune response by leukocytes. (haramonting) contains antioxidants that may prevent lung damage induced by allethrin-containing electric mosquito repellents.

Dispersion of surface floating plastic marine debris from Indonesian waters using hydrodynamic and trajectory models.

Plastic waste has become the most significant component of marine debris, while research on traces of marine plastic waste related to the condition of Indonesian waters is still limited. Therefore, this study examines the movement patterns of plastic marine debris in Indonesian waters. Simulations were carried out for one year (2013) using the HAMburg Shelf Ocean Model (hydrodynamic model) and Lagrange trajectory.

Determinants of sharia life insurance productivity in Indonesia.

This study examines the productivity and factors influencing the productivity of Sharia-compliant life insurance businesses in Indonesia over six years, from 2014 to 2019. A Two-Stage Malmquist Productivity Index was utilized. The first stage examined productivity using the Malmquist Productivity Index (MPI) method, while the second used the panel data regression method to identify the factors influencing productivity.

The effectiveness of chlorine dioxide gas in portable personal disinfectants to inhibit bacterial growth.

Disinfectants, especially air disinfectants, are necessary to prevent the potential spread of pathogens (bacteria and viruses) in the pandemic era and minimize the spread of pathogens. Some of the commercial disinfectant products that are often used generally contain chlorine dioxide (ClO) gas. This study tested the effectiveness of two different commercial disinfectants, a liquid stick disinfectant and a powder disinfection card, to carry out the disinfection of pathogenic bacteria in the environment.

TIMP2 and IGFBP-7 as Biomarkers For The Diagnosis of Acute Kidney Injury (AKI) in Post-operative Patients: An Evidence-Based Case Report.

Background: Acute kidney injury (AKI) is defined as a sudden reduction in kidney function which commonly occurs as a complication of major surgeries. It is traditionally diagnosed using serum creatinine elevation. AKI has relatively slow kinetics that makes it unable to diagnose at an earlier more reversible stage.

Effects of Ambient Temperature, Relative Humidity, and Precipitation on Diarrhea Incidence in Surabaya.

Background: Diarrhea remains a common infectious disease caused by various risk factors in developing countries. This study investigated the incidence rate and temporal associations between diarrhea and meteorological determinants in five regions of Surabaya, Indonesia.

Method: Monthly diarrhea records from local governmental health facilities in Surabaya and monthly means of weather variables, including average temperature, precipitation, and relative humidity from Meteorology, Climatology, and Geophysical Agency were collected from January 2018 to September 2020.

In Silico Study: Combination of α-Mangostin and Chitosan Conjugated with Trastuzumab against Human Epidermal Growth Factor Receptor 2.

Breast cancer is a type of cancer with the highest prevalence worldwide. Almost 10-30% of breast cancer cases are diagnosed as positive for HER2 (human epidermal growth factor receptor 2). The currently available treatment methods still exhibit many shortcomings such as a high incidence of side effects and treatment failure due to resistance.

Development and preliminary validity of an Indonesian mobile application for a balanced and sustainable diet for obesity management.

Background: Mobile applications such as personalized tracking tools and food choice aids may enhance weight loss programs. We developed and assessed client preferences for the content, user interface, graphics, and logic flow of a mobile application, and evaluated its validity for tracking compliance with weight control and making healthy and sustainable food choices.

Methods: Our four-stage study comprised formative research, application development, acceptance assessment, and validity.

Biodelignification of lignocellulose using ligninolytic enzymes from white-rot fungi.

Lignocellulose is the most abundant biomass available on earth, including wood and agricultural wastes such as rice straw, corn cobs, and oil palm empty bunches. The biopolymer content in lignocellulose has a great potential as feedstock for producing industrial raw materials such as glucose, sorbitol, xylose, xylitol, and other pharmaceutical excipients. Currently, scientists and governments agree that the enzymatic delignification method is an environmentally friendly green method to be applied.

The Potency of Lam. as Protective Agent in Cardiac Damage and Vascular Dysfunction.

Cardiac damage and vascular dysfunction due to underlying diseases, such as hypertension and cardiac thrombosis, or side effects from certain drugs may lead to critical illness conditions and even death. The phytochemical compounds in natural products are being prospected to protect the heart and vascular system from further damage. genus is a subtropical tree native to Asia and Africa, which includes 13 species; Lam.

Food safety knowledge, attitudes, and practices of food handlers at kitchen premises in the Port 'X' area, North Jakarta, Indonesia 2018.

Improper food handling can be a major cause of food contamination. To prevent food contamination, the food handler should have good knowledge, display a positive attitude, and practice proper food handling practices. This study aimed to evaluate the food safety and personal hygiene knowledge, attitudes, and practices of food handlers at kitchen premises in the Port 'X' area in North Jakarta, Indonesia.

Fatty acid binding protein 4 (FABP4) and metabolic-related parameters in systemic lupus erythematosus active and non-active episode.

Objective: To assess serum FABP4 and other metabolic-related parameters in Systemic Lupus Erythematosus (SLE) active and non-active episode.

Methods: Fifty-four SLE patients in Hasan Sadikin General Hospital, Bandung, Indonesia in 2018-2019 were recruited and serum samples were collected in their active and non-active episode status. Serum was analyzed for FABP4, leptin, glucose, and triglycerides.

Acetic Acid and Iodine Staining for Determining Malignancy in Solid Tumors.

Objective: Surgical margin is an important prognostic factor in solid cancer surgery. Frozen section (FS), the gold standard for intraoperative surgical margin evaluation, requires extensive waiting time and expensive FS devices. The purpose of this diagnostic study was to verify whether multi-staining (MS) method with acetic acid and iodine could be used to differentiate malignant and non-malignant lesions of solid tumor.

Spectroscopic Ellipsometry Characterization of As-Deposited and Annealed Non-Stoichiometric Indium Zinc Tin Oxide Thin Film.

A spectroscopic ellipsometry study on as-deposited and annealed non-stoichiometric indium zinc tin oxide thin films of four different compositions prepared by RF magnetron sputtering was conducted. Multi-sample analysis with two sets of samples sputtered onto glass slides and silicon wafers, together with the analysis of the samples onto each substrate separately, was utilized for as-deposited samples. Annealed samples onto the glass slides were also analyzed.

Electrical Properties of Amorphous Indium Zinc Tin Oxide Thin Film Transistor with Y₂O₃ Gate Dielectric.

High- Y₂O₃ thin films were investigated as the gate dielectric for amorphous indium zinc tin oxide (IZTO) thin-film transistors (TFTs). Y₂O₃ gate dielectric was deposited by radio frequency magnetron sputtering (RF-MS) under various working pressures and annealing conditions. Amorphous IZTO TFTs with SiO₂ as the gate dielectric showed a high field-effect mobility (μ) of 19.

Numerical study of tides in the Malacca Strait with a 3-D model.

Malacca Strait (MS) has an important role and potential for many countries. It is a major transportation route for oil and commodities across continents. In addition, various activities such as shipping, fishing, aquaculture, oil drilling, and energy are also carried out in MS.

Calcitriol Ameliorates Kidney Injury Through Reducing Podocytopathy, Tubular Injury, Inflammation and Fibrosis in 5/6 Subtotal Nephrectomy Model in Rats.

Chronic kidney diseases (CKDs) lead to end-stage renal diseases (ESRD) which are characterized by glomerulosclerosis, tubular injury, anemia, inflammation, and interstitial fibrosis. Vitamin D is known to have renal protective effects. However, its effects relate to low and high doses of Vitamin D in CKD model is still unknown.

Influence of Oxygen Partial Pressure on Radio Frequency Magnetron Sputtered Amorphous InZnSnO Thin Film Transistors.

Amorphous oxide semiconductors (AOS) have been studied extensively for the past decade as a possible alternative to polysilicon thin film transistors (TFTs). One such example is amorphous InZnSnO (IZTO), which was used in this study as an active channel layer for TFTs. A 30 nm-thick IZTO film was deposited using RF magnetron sputtering with various oxygen partial pressures, followed by annealing treatment in air at 350 °C.

Effect of the Active Channel Thickness Variation in Amorphous In-Zn-Sn-O Thin Film Transistor.

Ternary oxide thin films in the In₂O₃-ZnO-SnO₂ system were studied for potential applications in oxide semiconductor thin film transistors (TFTs). An amorphous In-Zn-Sn-O (a-IZTO) active channel layer was deposited by RF magnetron sputtering at room temperature on an ++ Si substrate. Films from a sintered ceramic target with a nominal chemical composition of In:Zn:Sn = 40:50:10 at.