Curative effect of Amorphophallus campanulatus (Roxb.) Blume. tuber on N-nitrosodiethylamine- induced hepatocellular carcinoma in rats.

In this study, we investigated the curative effect of Amorphophallus campanulatus tuber methanolic extract (ACME) on N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma (HCC) in experimental rats. All of the rats except those in the normal control group received 0.02% NDEA orally (2 mL, 5 days/week) for the first 20 weeks of the experiment.

Chemopreventive effect of Amorphophallus campanulatus (Roxb.) blume tuber against aberrant crypt foci and cell proliferation in 1, 2-dimethylhydrazine induced colon carcinogenesis.

Colorectal cancer is one of the leading causes of cancer death, both in men and women. This study investigated the effects of Amorphophallus campanulatus tuber methanolic extract (ACME) on aberrant crypt foci (ACF) formation, colonic cell proliferation, lipid peroxidative damage and the antioxidant status in a long term preclinical model of 1, 2-dimethylhydrazine (DMH) induced colon carcinogenesis in rats. Male Wistar rats were divided into six groups, viz.

Protective effect of Amorphophallus campanulatus (Roxb.) Blume. tuber against thioacetamide induced oxidative stress in rats.

Objective: To identify the phytochemical constituents of Amorphophallus campanulatus (A. campanulatus) tuber and to evaluate its antioxidant potential through in vitro and in vivo models.

Methods: Phytochemical screening and in vitro antioxidant activities of A.