Publications by authors named "Pustovitova T"

Memory impairment, headaches and vertigo are considered as initial appearances of chronic cerebral vascular disorder in patients with arterial hypertension (AH). The complex analysis of complaints, cognitive functioning, emotional state and MRI data was conducted in 60 patients with AH, mean age 58,4+/-7,8 years, without a history of stroke and 30 controls matched for age, sex and education. Impairment of cognitive functioning was assessed by the Psychiatric Status Scale (a short version), the Clock Drawing Test, tests of auditory and verbal memory, attention concentration, speed of test performance, speech fluency and spatial orientation.

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Combined antihypertensive therapy based on 2.5-5 mg of cilazapril (an angiotensin-converting enzyme inhibitor) to normalize arterial pressure (ABP) was studied in 22 patients (12 male, 10 female) aged 49-74 years (mean 63 +/- 7 years) with stroke (18 patients) or transient ischemic attacks (three patients). Magnetic resonance tomography (MRT) including perfusion studies, along with neuropsychological studies and assessment of emotional status (Beck depression inventory, Spielberger anxiety scale), were performed before and after treatment.

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To normalize arterial pressure (AP), combined antihypertensive therapy, basing on intake of 2,5-5 mg cilazapril, inhibitor of angiotensin-converting enzyme (IACE), was administered to 22 patients, 12 men, 10 women, aged from 49 to 74 years, mean age 63 +/- 7 years, who survived stroke (18 patients) or transitory ischemic attack (3 patients). Magnetic resonance tomography (MRT), i.e.

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Aortic elasticity was studied in aged patients with mild and moderate arterial hypertension using magnetic resonance imaging. The analysis of changes in cross section area (CSA) of the ascending aorta in systole has shown that in some patients maximal CSA occurs in different systolic phases while in the other patients CSA remains unchanged. Calculation with the elasticity rate proved that patients with maximal aortic diameter at the beginning of the systole have maximal aortic elasticity while those with minimal changes in aortic diameter in the course of the systole have minimal elasticity.

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Magnetic resonance tomography was performed to examine the kidneys, brain, adrenals, vessels, and heart in 110 patients with malignant arterial hypertension (MAH). The findings were compared with those of the examination of healthy subjects and patients with benign hypertensive disease (BHD). As compared to the controls, all the MAH patients had changes in the target organs, however, their nature and magnitude varied with under underlying MAH disease.

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MR-tomography was used for the investigation of 38 healthy persons aged 17 to 48 with normal BP values without any renal and adrenal pathology (kidneys were investigated in 25 persons, adrenal glands--in 16). A BMT-1100 MR-tomograph (Brucker, FRG) was used for investigation. The authors stress noninvasiveness of the new method and its practical value.

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The paper is devoted to the use of a new method of nuclear magnetic resonance tomography (MR tomography) in the diagnosis of diseases of the adrenal glands developing with the syndrome of total and partial hypercorticism. A MR tomograph with resistive magnet (0.234 T) was employed.

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To study the potentialities of MR tomography in the diagnosis of chromaffin tissue tumors and to elaborate a number of quantitative diagnostic criteria, 26 patients with pheochromocytoma were examined. All the patients were subjected to x-ray computer-aided tomography of the adrenals. In 24 of them, the diagnosis was completely confirmed on histological examination of the excised tumor.

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99 patients with arterial hypertension (AH) were studied: 17 patients with pheochromocytoma, 37 with aldosteronoma, 4 with corticosteroma, 38 with essential hypertension. Control group included 16 healthy subjects. The investigation was performed by means of a NMR-tomograph BMT-1100 ("Brucker", FRG) in axial and frontal planes according to Spin Echo (SE) technique with TR = 2.

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MR-tomography was employed for examination of 41 patients with arterial hypertension (AH). Aldosteroma was diagnosed in 11 patients, pheochromocytoma in 4 patients, paraganglioma in one patient. 25 patients with essential hypertension (EH) were entered into the comparison group and 16 healthy persons into the control group.

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A new method of tomography based on the principle of nuclear magnetic resonance (NMR-tomography) was used to determine the heart size in experimental animals. The study involved 25 rabbits and NMR-tomograms of their hearts were obtained both in situ and on the isolated heart. The results obtained were compared with the morphometric findings.

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