Publications by authors named "Purwa Doke"
Article Synopsis
- Pulmonary rehabilitation (PR) was implemented for COVID-19 patients experiencing long-term effects to assess its impact on their functional capacity and health-related quality of life (HRQOL).
- The study involved 155 post-COVID patients undergoing a pre and post-assessment that included a six-minute walk test, focusing on various interventions like education, exercise, and strength training, conducted over eight weeks.
- Results indicated significant improvements in resting pulse rate, oxygen saturation, walking distance, and various HRQOL domains, highlighting PR as effective for enhancing the quality of life in post-COVID patients.
Purpose: To assess modulation of neutralizing antibody titers in COVID-19 patients and understand association of variables such as age, presence of comorbidity, BMI and gender with antibody titers.
Methods: Patients (n = 100) diagnosed from 20th March 2020 to 17th August 2020 and treated at two large hospitals from Pune, India were included and followed up (clinical and serologic) for varied periods. IgG-anti-SARS-CoV-2 (Spike protein-based ELISA) and neutralizing antibody titers (NAb, PRNT) were determined in all the samples.
Understanding of the basis for severity and fatal outcome of SARS-CoV-2 infection is of paramount importance for developing therapeutic options and identification of prognostic markers. So far, accumulation of neutrophils and increased levels of pro-inflammatory cytokines are associated with disease severity in COVID-19 patients. In this study, we aimed to compare circulatory levels of neutrophil secretory proteins, alpha-defensins (DEFA1), calprotectin (S100A8/A9), and myeloperoxidase (MPO) in COVID-19 patients with different clinical presentations.
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