Anticancer effect of Moringa oleifera in oral squamous cell carcinoma: a systematic review.

Background And Objective: Oral squamous cell carcinoma is the most common form of mouth cancer. As plant-based medicines become increasingly popular, Moringa oleifera has been studied extensively for its plant-based components, and health benefits. The present review examined the anticancer effects of Moringa oleifera extracts on Oral squamous cell carcinoma.

Assessment of gamma absorbed doses and radiological risk indexes from soil radioactivity around the phosphate area in south Tunisia.

Human beings are constantly exposed to the radiations coming from the environment. This work assesses the radiological hazards of natural radioactivity in soil samples taken at four locations around the phosphate area in south Tunisia. Concentrations of primordial radionuclides were measured by gamma spectrometer using an HPGe detector.

The Association Between Alzheimer's Disease and Epilepsy: A Narrative Review.

Several studies have established the two-way relationship between the sporadic and familial forms of Alzheimer's disease (AD) and epilepsy. However, a more robust connection exists between epilepsy and early onset familial AD (EOFAD). Still, the mechanisms underlying the same are not yet fully understood.

Determination of Organically Bound Tritium (OBT) Concentration in Fish by Thermal Oxidation and Liquid Scintillation Counting Method.

Effluents containing tritium (H) dispersed into the fresh water or marine environment from nuclear facilities can be taken up by biota. Aquatic and marine organisms are among the important pathways through which tritium can enter into the human body, and hence, assessment of the extent of pollution of these ecosystems is very important for radiation dose assessments. Tritium present in environmental matrices can be classified as tissue-free water tritium (TFWT) and organically bound tritium (OBT).

Cone Beam Computed Tomography-aided Endodontic Management of Second Maxillary Molar with Two Separate Palatal Roots: A Case Report.

An infected human root canal system harbors harmful microbiota that needs to be eliminated by root canal therapy. But the human root canal system is known to have a complex anatomy. Hence, the knowledge of a possibly aberrant anatomy is deemed necessary before carrying out a root canal therapy.

Graphene modified glassy carbon sensor for the determination of aspirin metabolites in human biological samples.

A graphene modified glassy carbon (GR/GCE) sensor has been developed for the determination of aspirin metabolites 2,3- and 2,5-dihydroxybenzoic acids (2,3- and 2,5-DHB). The modified sensor was characterized by Field Emission Scanning Electron Microscopy and Electrochemical Impedance Spectroscopy. The electrochemical behavior of 2,3- and 2,5-DHB was investigated by cyclic and square wave voltammetry.

Off label use of lithium in the treatment of Huntington's disease: A case series.

Huntington's disease is characterized by choreic movements, psychiatric disorders, striatal atrophy with selective small neuronal loss, and autosomal dominant inheritance. The genetic abnormality is CAG expansion in Huntingtin gene. Newer therapeutic strategies are evolving to treat this progressive disorder.

The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes.

Cocaine, a potent stimulant of the central nervous system, owes its reinforcing and stimulant properties to its ability to inhibit monoamine uptake systems such as the Dopamine Transporter (DAT), and the Serotonin Transporter (SERT) located on presynaptic neurons in the striatum. The search for pharmacotherapies for cocaine addiction has focused on the design of compounds that bind selectively to the DAT and manifest slow onset of stimulatory action with long duration of action. We had reported that 3-aryl-2-carbomethoxy-8-thiabicyclo[3.

Efficient asymmetric synthesis of silanediol precursors from 1,5-dihydrosiloles.

Dihydrosiloles are easily prepared from 1,3-dienes and dichlorosilanes, even on kilogram scale. Asymmetric hydroboration of a 3-alkyl-1,5-dihydrosilole, prepared from a 2-alkyl-1,3-diene, followed by treatment with aqueous HF results in Peterson fragmentation, forming optically active 3-alkyl-4-fluorosilyl-1-butenes. The fluorosilanes are stable to moisture but very reactive toward nucleophiles.

A serendipitous discovery of antifreeze protein-specific activity in C-linked antifreeze glycoprotein analogs.

Structurally diverse carbon-linked (C-linked) analogs of antifreeze glycoprotein (AFGP) have been prepared via linear or convergent solid phase synthesis. These analogs range in molecular weight from approx 1.5-4.