[Report of a new case of Cobb syndrome. Meningo-spinal cutaneous angiomatosis].

The authors present a 47 years old female patient with cutaneomeningospinal angiomatosis or Cobb's syndrome of thoracic location. This entity, included in the primarily mesodermic phacomatose, is extremely rare, and only 17 cases have been sufficiently documented in the literature on the subject. The rare association with vertebral haemangioma of the same metameric level was present in this patient.

[Jugular chemodectoma with Garcin syndrome].

The authors present an exceptional case of chemodectoma jugulare with important invasion of the skull base involving all the cranial nerves on one side and conforming Garcin's syndrome. Practically all the possible ways of spreading were followed by the tumor, with involvement of the posterior, middle and anterior fossas of the skull base and also orbit, middle ear and neck. The clinical and histopathological difficulties in the diagnosis, especially when the chemodectoma has only neurological signs, are stressed.

[Tumors of the sellar region and the cavernous sinus. Evaluation of diagnostic procedures and therapeutic orientation].

Two cases of infrequently seen tumors of the cavernous sinus and the clivus regions are presented. One of them was a chordoma and the other, a myeloma, and both were approached by the transphenoidal route. The clinical picture and the diagnostic procedures are reviewed, and the several surgical approaches to these regions are discussed.

[Actinomycotic cerebral abscess. Apropos of a case].

A case of an actinomycotic brain abscess in an adult patient apparently free of systemic infection is presented. The rarity of this etiology of brain abscess is underlined. The patient was treated by complete surgical excision and prolonged antibiotic therapy with penicillin.

[Termino-lateral anastomosis of the carotid of the rat. Histological evaluation of permeability in relation to the number of suture stitches and the thread used].

A histological study of end-to-side anastomosis on the carotid arteries of the rat, is presented comparing the results according to the type of suture material and the number of stitches. Two groups of 5 animals were studied. Group "A" in which the 11-0 monofilament nylon (18 microns; needle of 70 microns) was utilized with an average of 11 stitches; and group "B" corresponding to the 10-0 nylon (25 microns; needle of 100 microns) with an average of 8 stitches.

[Dysplastic gangliocytoma of the cerebellum or Lhermittee-Duclos disease].

Lhermitte-Duclós disease is an infrequent condition of which there are only 37 cases described in the literature. Although presently considered as a displasic process, its clinical presentation is of a typical posterior fossa tumour and should be treated as such. Even though it is a benign growth there are only 7 cases described with postoperative survival.

[Clinicopathological analysis of fatal cerebellar hematomas].

An analysis is made of the clinical observations and pathological findings in 16 fatal cerebellar hematomas admitted at the Instituto de Neurología in Montevideo, over a period of 23 years. The absence of definitive lesions of the brainstem in the majority of cases, in spite of the rich symptomatology of brainstem disfunction (horizontal gaze palsies, vegetative syndrome decerebrate movements) is stressed, as well as the rapid evolution of those cases with intraventricular haemorrhage. Missed clinical diagnosis was also frequent in severely ill patients.

[Brain aging. Ultrastructural study of changes in man and laboratory animals].

The authors present a study on ultrastructural changes observed in aged human and animal brain. These changes are analyzed and compared with those described in classic optic microscopy and with those observed in experimental models of the same lesions.

[Embolization with adipose tissue (author's transl)].

The authors present their animal experimental work on adipose tissue as an occlusive agent, using the renal and carotid areas as parenchyma in which to test its effect. Work was planned in four series: the first with a survival rate of 24 to 72 h, the second with a survival rate of 7 to 18 days, the third, 45 to 58 days, and the fourth, 58 to 90 days. Angiographic and anatomopathologic postembolization controls were performed, thus supplying conclusive radiologic and histologic documentation on the embolization material under study.

[A case of cerebral microglioma].

The authors present the first national observation of a microgliosarcoma. The patient, a woman of 57 years old, was admitted with the clinical and paraclinical diagnosis of an intracranial mass occupying lesion. Surgical excision was incomplete, and postoperative radiotherapy was undertaken.