Publications by authors named "Purificacion Ramirez-Martin"
Pulmonary embolism (PE), the most severe form of presentation of venous thromboembolic disease (VTE), currently represents a foremost healthcare issue due to its high impact in terms of morbidity, mortality, costs, and resource consumption. Early mortality associated with PE is primarily due to hemodynamic instability, exacerbation of pre-existing conditions, or major complications of antithrombotic therapies. Beyond the risk of death, there are relevant complications related to PE, such as bleedings, VTE recurrences, and persistence of residual respiratory symptoms; the latter complication related to PE is mainly characterized by two entities, chronic thromboembolic pulmonary hypertension and chronic thromboembolic disease.
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- Asthma exacerbations significantly contribute to global health issues, with the GEMAS study focusing on understanding the genetic and microbiome factors behind severe asthma attacks.
- The study involved recruiting 137 asthma patients who had experienced severe exacerbations and 120 controls without such episodes, gathering extensive biological, clinical, and demographic data from various hospitals in Spain.
- Results indicated that patients with exacerbations had worse lung function and uncontrolled asthma compared to controls, highlighting the importance of defining phenotypes for further research into potential predictive biomarkers.